UniProt Accession

 RS21_DROME; O76927; A4V027 

Genbank Protein ID

 AJ009557; AE014134; AE014134; AE014134; BT015189 

Genbank Nucleotide ID

 CAA08751.1; AAF51191.1; AAN10392.1; AAN10393.2; AAT94418.1 

Protein Name

 40S ribosomal protein S21 

Protein Synonyms/Alias

 Overgrown hematopoietic organs at 23B 

Gene Name

 RpS21 

Gene Synonyms/Alias

 oho23B; CG2986 

Created Date

 July 27, 2013 

Organism

 Drosophila melanogaster (Fruit fly) 

NCBI Taxa ID

 7227 

Lysine Modification

Position	Peptide	Type	References
81	KKDGIITKNF*****	acetylation	[1]

Reference

 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 

Functional Description

 May be an associated component of the ribosome rather than a core structural subunit. May act as a translation initiation factor. Has a role in regulation of cell proliferation in the hematopoietic organs and the imaginal disks of larva. 

Sequence Annotation

  

Keyword

 3D-structure; Alternative splicing; Complete proteome; Cytoplasm; Developmental protein; Reference proteome; Ribonucleoprotein; Ribosomal protein; rRNA processing; Translation regulation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 83 AA 

Protein Sequence

Gene Ontology

 GO:0022627; C:cytosolic small ribosomal subunit; IBA:RefGenome.
 GO:0043022; F:ribosome binding; IPI:UniProtKB.
 GO:0003735; F:structural constituent of ribosome; IDA:FlyBase.
 GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:RefGenome.
 GO:0000461; P:endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:RefGenome.
 GO:0048542; P:lymph gland development; IMP:FlyBase.
 GO:0042127; P:regulation of cell proliferation; IMP:UniProtKB.
 GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
 GO:0006414; P:translational elongation; IBA:RefGenome. 

Interpro

 IPR001931; Ribosomal_S21e.
 IPR018279; Ribosomal_S21e_CS. 

Pfam

 PF01249; Ribosomal_S21e 

SMART

  

PROSITE

 PS00996; RIBOSOMAL_S21E 

PRINTS