CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038513
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 TBC1 domain family member 1 
Protein Synonyms/Alias
  
Gene Name
 Tbc1d1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
957KTNSSLRKQNLDLLEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1033 AA 
Protein Sequence
MSPLFSWVAK VPEIISSIRQ AGKIARQEEL RCPSEFDDTF AKKFEVLFCG RVTVAHKKAP 60
PALIDECIEK FNHVSCGRRT DWEAPTGQPS APGPRPMRKS FSQPGLRSLA FRKEFQDASL 120
RSSTFSSFDN DIENHLIGGH NVVQPTDMEE NRTMLFTIGQ SEVYLISPDT KKIALEKNFK 180
EISFCSQGIR HVDHFGFICR ECSGGGSGGF HFVCYVFQCT NEALVDEIMM TLKQAFTVAA 240
VQQTAKAPAQ LCEGCPLQGL HKLCERIEGM NSSKTKLELQ KHLTTLTNQE QATIFEEVQK 300
LRPRNEQREN ELIISFLRCL YEEKQKEHSH TGEPKQTLQV AAENIGSDLP PSASRFRLDS 360
LKNRAKRSLT ESLESILSRG NKARGLQDHS ASVDLDSSTS STLSNTSKEL SMGDKEAFPV 420
SETSFKLLGS SDDLSSDSEG HIAEESALLS PQQAFRRRAN TLSHFPVECP APPEPAQSSP 480
GVSQRKLMRY HSVSTETPHE RKDFESKANH LGDTDGTPVK TRRHSWRQQI FLRVATPQKA 540
CDSPSRYEDY SELGELPPRS PLEPVCEDGP FGPVQEEKRK TSRELRELWK KAILQQILLL 600
RMEKENQKLQ ASENDLLNKR LKLDYEEITP CLKEVTTVWE KMLSTPGRSK IKFDMEKVHS 660
AVGQGVPRHH RGEIWKFLAE QFHLKHPFPS KQQPKDVPYK ELLKKLTSQQ HAILIDLGRT 720
FPTHPYFSAQ LGAGQLSLYN ILKAYSLLDQ EVGYCQGLSF VAGILLLHMS EEEAFKMLKF 780
LMFDMGLRKQ YRPDMIILQI QMYQLSRLLH DYHRDLYNHL EEHEIGPSLY AAPWFLTVFA 840
SQFPLGFVAR VFDMIFLQGS EVIFKVALSL LGSHKPLILQ HENLETIVDF IKNTLPNLGL 900
VQMEKTISQV FEMDIAKQLQ AYEVEYHVLQ EELIESSPLS DNQRMEKLEK TNSSLRKQNL 960
DLLEQLQVAN ARIQSLEATV EKLLTSESKL KQAALTLEVE RSALLQMVEE LRRQSARPST 1020
PEPDCTQLEP TGD 1033 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
 GO:0032851; P:positive regulation of Rab GTPase activity; IEA:GOC. 
Interpro
 IPR021785; DUF3350.
 IPR011993; PH_like_dom.
 IPR006020; PTyr_interaction_dom.
 IPR000195; Rab-GTPase-TBC_dom. 
Pfam
 PF11830; DUF3350
 PF00640; PID
 PF00566; RabGAP-TBC 
SMART
 SM00462; PTB
 SM00164; TBC 
PROSITE
 PS01179; PID
 PS50086; TBC_RABGAP 
PRINTS