CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026410
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Zinc finger MYM-type protein 2 
Protein Synonyms/Alias
  
Gene Name
 ZMYM2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
318PAAIEELKSKVSSDAubiquitination[1, 2]
460TYGVNAWKHWVKTRQubiquitination[1]
479LLVLDELKSSKSVKLubiquitination[1, 3]
482LDELKSSKSVKLKEDubiquitination[1]
485LKSSKSVKLKEDLLSubiquitination[1]
539YLCGSNRKDNIFIDPubiquitination[1, 2]
557TFEQELNKILRSWQPubiquitination[1]
610NTKYFGLKTVEQHLRubiquitination[1]
629TVFRHWKKNPLTMENubiquitination[1]
637NPLTMENKACLRYQVubiquitination[1]
655CGTDNEDKITTGKRKubiquitination[1]
660EDKITTGKRKHEDDEacetylation[2]
660EDKITTGKRKHEDDEubiquitination[1, 2]
662KITTGKRKHEDDEPVubiquitination[1]
685NPSRCPVKMFECYLSubiquitination[1]
693MFECYLSKSPQNLNQubiquitination[1, 3]
742LVRVLLVKDIYDKDNubiquitination[1]
747LVKDIYDKDNYELDEubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 757 AA 
Protein Sequence
MQSSPNGQFV APSDIQLKCN YCKNSFCSKP EILEWEASLH QFCSKTCSDD YKKLHCIVTY 60
CEYCQEEKTL HETVNFSGVK RPFCSEGCKL LYKQDFARRL GLRCVTCNYC SQLCKKGATK 120
ELDGVVRDFC SEDCCKKFQD WYYKAARCDC CKSQGTLKER VQWRGEMKHF CDQHCLLRFY 180
CQQNEPNMTT QKGPENLHYD QGCQTSRTKM TGSAPPPSPT PNKEMKNKAV LCKPLTMTKA 240
TYCKPHMQTK SCQTDDTWRT EYVPVPIPVP VYIPVPMHMY SQNIPVPTTV PVPVPVPVFL 300
PAPLDSSEKI PAAIEELKSK VSSDALDTEL LTMTDMMSED EGKTETTNIN SVIIETDIIG 360
SDLLKNSDPE TQSSMPDVPY EPDLDIEIDF PRAAEELDME NEFLLPPVFG EEYEEQPRPR 420
SKKKGAKRKA VSGYQSHDDS SDNSECSFPF KYTYGVNAWK HWVKTRQLDE DLLVLDELKS 480
SKSVKLKEDL LSHTTAELNY GLAHFVNEIR RPNGENYAPD SIYYLCLGIQ EYLCGSNRKD 540
NIFIDPGYQT FEQELNKILR SWQPSILPDG SIFSRVEEDY LWRIKQLGSH SPVALLNTLF 600
YFNTKYFGLK TVEQHLRLSF GTVFRHWKKN PLTMENKACL RYQVSSLCGT DNEDKITTGK 660
RKHEDDEPVF EQIENTANPS RCPVKMFECY LSKSPQNLNQ RMDVFYLQPE CSSSTDSPVW 720
YTSTSLDRNT LENMLVRVLL VKDIYDKDNY ELDEDTD 757 
Gene Ontology
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR021893; DUF3504.
 IPR011017; TRASH_dom.
 IPR010507; Znf_MYM. 
Pfam
 PF12012; DUF3504
 PF06467; zf-FCS 
SMART
 SM00746; TRASH 
PROSITE
  
PRINTS