CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009542
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 60S ribosomal protein L23a 
Protein Synonyms/Alias
  
Gene Name
 Rpl23a 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
14KEAPAPPKAEAKAKAacetylation[1]
70KSAPRRNKLDHYAIIacetylation[1]
134LIRPDGEKKAYVRLAacetylation[1]
Reference
 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123
Functional Description
 This protein binds to a specific region on the 26S rRNA (By similarity). 
Sequence Annotation
 MOD_RES 2 2 N,N,N-trimethylalanine; by NTM1.
 MOD_RES 45 45 Phosphothreonine (By similarity).  
Keyword
 Complete proteome; Methylation; Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding; rRNA-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 156 AA 
Protein Sequence
MAPKAKKEAP APPKAEAKAK ALKAKKAVLK GVHSHKKKKI RTSPTFRRPK TLRLRRQPKY 60
PRKSAPRRNK LDHYAIIKFP LTTESAMKKI EDNNTLVFIV DVKANKHQIK QAVKKLYDID 120
VAKVNTLIRP DGEKKAYVRL APDYDALDVA NKIGII 156 
Gene Ontology
 GO:0005634; C:nucleus; ISS:UniProtKB.
 GO:0005840; C:ribosome; IEA:UniProtKB-KW.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
 GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
 GO:0006412; P:translation; IEA:InterPro. 
Interpro
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR019985; Ribosomal_L23.
 IPR012678; Ribosomal_L23/L15e_core_dom.
 IPR001014; Ribosomal_L23/L25_CS.
 IPR005633; Ribosomal_L23/L25_N.
 IPR013025; Ribosomal_L25/23. 
Pfam
 PF00276; Ribosomal_L23
 PF03939; Ribosomal_L23eN 
SMART
  
PROSITE
 PS00050; RIBOSOMAL_L23 
PRINTS