CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011965
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Vesicle transport protein SEC20 
Protein Synonyms/Alias
 BCL2/adenovirus E1B 19 kDa protein-interacting protein 1; Transformation-related gene 8 protein; TRG-8 
Gene Name
 BNIP1 
Gene Synonyms/Alias
 NIP1; SEC20L; TRG8 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
48TELNTKVKEKFQQLRubiquitination[1]
154IAIDNLEKAELLQGGubiquitination[1]
171LRQRKTTKESLAQTSubiquitination[1]
221LDANEEFKSMSGTIQubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER. Required for maintenance of ER network. Implicated in the suppression of cell death. May be involved in mitochondrial autophagy. 
Sequence Annotation
  
Keyword
 Alternative splicing; Apoptosis; Autophagy; Coiled coil; Complete proteome; Endoplasmic reticulum; ER-Golgi transport; Membrane; Mitochondrion; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix; Transport; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 228 AA 
Protein Sequence
MAAPQDVHVR ICNQEIVKFD LEVKALIQDI RDCSGPLSAL TELNTKVKEK FQQLRHRIQP 60
VLYQRAFIWT ASTFFFKLTY SLTDFSSTQH DFNSPTTPVT FSDLEQLAKE QDKESEKQLL 120
LQEVENHKKQ MLSNQASWRK ANLTCKIAID NLEKAELLQG GDLLRQRKTT KESLAQTSST 180
ITESLMGISR MMAQQVQQSE EAMQSLVTSS RTILDANEEF KSMSGTIQLG RKLITKYNRR 240
ELTDKLLIFL ALALFLATVL YIVKKRLFPF L 271 
Gene Ontology
 GO:0030176; C:integral to endoplasmic reticulum membrane; TAS:HGNC.
 GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
 GO:0005635; C:nuclear envelope; IDA:UniProtKB.
 GO:0031201; C:SNARE complex; IDA:HGNC.
 GO:0006915; P:apoptotic process; IPI:MGI.
 GO:0006914; P:autophagy; IEA:UniProtKB-KW.
 GO:0016320; P:endoplasmic reticulum membrane fusion; IMP:HGNC.
 GO:0007029; P:endoplasmic reticulum organization; IMP:HGNC.
 GO:0006917; P:induction of apoptosis; IMP:HGNC.
 GO:0043066; P:negative regulation of apoptotic process; TAS:UniProtKB.
 GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW. 
Interpro
 IPR005606; Sec20. 
Pfam
 PF03908; Sec20 
SMART
  
PROSITE
  
PRINTS