CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040816
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Interferon-induced GTP-binding protein Mx1, N-terminally processed 
Protein Synonyms/Alias
  
Gene Name
 MX1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
31GDATVAQKNPGSVAEubiquitination[1]
87TRCPLVLKLKKLVNEubiquitination[1]
90PLVLKLKKLVNEDKWubiquitination[1]
96KKLVNEDKWRGKVSYubiquitination[1]
174QPADIGYKIKTLIKKubiquitination[1]
250NLVFHLKKGYMIVKCubiquitination[1]
294RDLLEEGKATVPCLAubiquitination[1]
409GHKILSRKIQKFENQubiquitination[1]
412ILSRKIQKFENQYRGubiquitination[1]
436RTFETIVKQQIKALEubiquitination[1]
467AFTDVSIKNFEEFFNubiquitination[1]
482LHRTAKSKIEDIRAEubiquitination[1]
608DTYSWLLKERSDTSDubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; GTP-binding; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 639 AA 
Protein Sequence
MVVSEVDIAK ADPAAASHPL LLNGDATVAQ KNPGSVAENN LCSQYEEKVR PCIDLIDSLR 60
ALGVEQDLAL PAIAVIGIVT RCPLVLKLKK LVNEDKWRGK VSYQDYEIEI SDASEVEKEI 120
NKAQNAIAGE GMGISHELIT LEISSRDVPD LTLIDLPGIT RVAVGNQPAD IGYKIKTLIK 180
KYIQRQETIS LVVVPSNVDI ATTEALSMAQ EVDPEGDRTI GILTKPDLVD KGTEDKVVDV 240
VRNLVFHLKK GYMIVKCRGQ QEIQDQLSLS EALQREKIFF ENHPYFRDLL EEGKATVPCL 300
AEKLTSELIT HICKSLPLLE NQIKETHQRI TEELQKYGVD IPEDENEKMF FLIDKVNAFN 360
QDITALMQGE ETVGEEDIRL FTRLRHEFHK WSTIIENNFQ EGHKILSRKI QKFENQYRGR 420
ELPGFVNYRT FETIVKQQIK ALEEPAVDML HTVTDMVRLA FTDVSIKNFE EFFNLHRTAK 480
SKIEDIRAEQ EREGEKLIRL HFQMEQIVYC QDQVYRGALQ KVREKELEEE KKKKSWDFGA 540
FQSSSATDSS MEEIFQHLMA YHQEASKRIS SHIPLIIQFF MLQTYGQQLQ KAMLQLLQDK 600
DTYSWLLKER SDTSDKRKFL KERLARLTQA RRRLAQFPG 639 
Gene Ontology
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; IEA:InterPro.
 GO:0006184; P:GTP catabolic process; IEA:GOC. 
Interpro
 IPR022812; Dynamin.
 IPR000375; Dynamin_central.
 IPR001401; Dynamin_GTPase.
 IPR003130; GED.
 IPR020850; GTPase_effector_domain_GED.
 IPR015577; Interferon-induced_Mx.
 IPR027417; P-loop_NTPase. 
Pfam
 PF01031; Dynamin_M
 PF00350; Dynamin_N
 PF02212; GED 
SMART
 SM00053; DYNc
 SM00302; GED 
PROSITE
 PS51388; GED 
PRINTS
 PR00195; DYNAMIN.