CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010483
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Succinyl-CoA ligase [ADP-forming] subunit beta 
Protein Synonyms/Alias
 Succinyl-CoA synthetase subunit beta; SCS-beta; Vegetative protein 63; VEG63 
Gene Name
 sucC 
Gene Synonyms/Alias
 BSU16090 
Created Date
 July 27, 2013 
Organism
 Bacillus subtilis (strain 168) 
NCBI Taxa ID
 224308 
Lysine Modification
Position
Peptide
Type
References
9NIHEYQGKEVLRKYGacetylation[1]
105IEEGCDIKKEYYIGLacetylation[1]
171AFAINIPKELVGKAAacetylation[1]
179ELVGKAAKFMLGLYKacetylation[1]
358GTNVDLGKKILSESGacetylation[1]
Reference
 [1] The acetylproteome of Gram-positive model bacterium Bacillus subtilis.
 Kim D, Yu BJ, Kim JA, Lee YJ, Choi SG, Kang S, Pan JG.
 Proteomics. 2013 May;13(10-11):1726-36. [PMID: 23468065] 
Functional Description
  
Sequence Annotation
 DOMAIN 9 244 ATP-grasp.
 NP_BIND 35 108 ATP (By similarity).
 METAL 197 197 Magnesium or manganese (By similarity).
 METAL 199 199 Magnesium or manganese (By similarity).
 MOD_RES 220 220 Phosphoserine.  
Keyword
 ATP-binding; Complete proteome; Direct protein sequencing; Ligase; Magnesium; Manganese; Metal-binding; Nucleotide-binding; Phosphoprotein; Reference proteome; Tricarboxylic acid cycle. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 385 AA 
Protein Sequence
MNIHEYQGKE VLRKYGVSVP EGKVAFTAEE AVESAKSLSS SVYVVKAQIH AGGRGKAGGV 60
KIAKSLDEVK AYAEELLGKT LVTHQTGPDG QVIKRLLIEE GCDIKKEYYI GLVLDRATSR 120
IVLMASEEGG TEIEEVAEKT PEKIKKAVID PAVGLQGYQA REIAFAINIP KELVGKAAKF 180
MLGLYKAFVE KDCSIAEINP LVVTGDGNVM ALDAKLNFDS NALYRQKDIM EYRDLDEEDP 240
KEIEASKYDL SYISLDGNIG CMVNGAGLAM STMDIIKHYG GEPANFLDVG GGATAEKVTE 300
AFKIILSDQN VKGIFVNIFG GIMKCDVIAE GVVEATRQVG LTLPLVVRLE GTNVDLGKKI 360
LSESGLNITS AESMADGAQK IVSLV 385 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:HAMAP.
 GO:0000287; F:magnesium ion binding; IEA:HAMAP.
 GO:0030145; F:manganese ion binding; IEA:HAMAP.
 GO:0004775; F:succinate-CoA ligase (ADP-forming) activity; IEA:HAMAP.
 GO:0006099; P:tricarboxylic acid cycle; IEA:HAMAP. 
Interpro
 IPR011761; ATP-grasp.
 IPR013650; ATP-grasp_succ-CoA_synth-type.
 IPR013815; ATP_grasp_subdomain_1.
 IPR013816; ATP_grasp_subdomain_2.
 IPR005811; CoA_ligase.
 IPR017866; Succ-CoA_synthase_bsu_CS.
 IPR005809; Succ_CoA_synthase_bsu.
 IPR016102; Succinyl-CoA_synth-like. 
Pfam
 PF08442; ATP-grasp_2
 PF00549; Ligase_CoA 
SMART
  
PROSITE
 PS50975; ATP_GRASP
 PS01217; SUCCINYL_COA_LIG_3 
PRINTS