| Tag | Content |
|---|
| CPLM ID | CPLM-027449 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Eukaryotic translation initiation factor 3 subunit D |
Protein Synonyms/Alias | eIF3d; Eukaryotic translation initiation factor 3 subunit 7 |
Gene Name | PF10_0077 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Plasmodium falciparum (isolate 3D7) |
NCBI Taxa ID | 36329 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 185 | IIKIDNLKVEDLFFK | acetylation | [1] |
|
Reference | [1] Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic development. Miao J, Lawrence M, Jeffers V, Zhao F, Parker D, Ge Y, Sullivan WJ Jr, Cui L. Mol Microbiol. 2013 Aug;89(4):660-75. [ PMID: 23796209] |
Functional Description | Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome (By similarity). |
Sequence Annotation | |
Keyword | Complete proteome; Cytoplasm; Initiation factor; Protein biosynthesis; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 543 AA |
Protein Sequence | MSSFNLVGVI NNRTWGPDSK NEELVNYCMP DIKKYQFEPS MKFERIGKVC DFTMNSYQKN 60
TKDINKNSND VNAFEEELQF QTVDLRTGQK QKGSIFNKKK IHNKQNTTQA FTQKQQEEDN 120
LYSSRIKTAE QKKQKLLQQA KTARINARHR IFTEWSIEPT PLWTVECEIM FNELPKKIIK 180
IDNLKVEDLF FKGKSLFYDK KIENINVKNP PLLFHHTKEG INLIPKTKED HNLINILNNE 240
NKNKIISNEE DPNNINNIIV ISTDQILSCL MSCVQSKYSW HLLIKKKGNQ IIIDKDDDSI 300
IDLLTVNENS IDAPTQDNEN KINSLQALGI EAVKINQRFR KQVILKNDIA EEFEPGNFNI 360
KNIKINDILY RYRKFQIPPL VQSNNKKTYT LITRGEIHSQ IKGLNKSYVY VCALNEYDIK 420
SHKNWRSQIE NQKGALLANE IRNNTSKLQK FISQALLSGC DDVKLGFISR KNANDPDNHH 480
ILSIQSHKTK DLSTQIGLKY DNMWGIFRFV IDNLADKPNG NYVILKDPLK PLLRLYCTHE 540
DSN 543 |
Gene Ontology | GO:0016282; C:eukaryotic 43S preinitiation complex; IEA:HAMAP. GO:0033290; C:eukaryotic 48S preinitiation complex; IEA:HAMAP. GO:0005852; C:eukaryotic translation initiation factor 3 complex; ISS:GeneDB_Pfalciparum. GO:0003743; F:translation initiation factor activity; IEA:HAMAP. GO:0001731; P:formation of translation preinitiation complex; IEA:HAMAP. GO:0006446; P:regulation of translational initiation; IEA:HAMAP. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |