CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023697
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Translation machinery-associated protein 7 
Protein Synonyms/Alias
 Coiled-coil domain-containing protein 72 
Gene Name
 TMA7 
Gene Synonyms/Alias
 CCDC72; HSPC016; HSPC330 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
27KEMDEEDKAFKQKQKacetylation[1]
27KEMDEEDKAFKQKQKubiquitination[2]
32EDKAFKQKQKEEQKKubiquitination[2]
39KQKEEQKKLEELKAKubiquitination[3]
50LKAKAAGKGPLATGGubiquitination[2, 3, 4]
Reference
 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [4] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965
Functional Description
  
Sequence Annotation
  
Keyword
 Coiled coil; Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 64 AA 
Protein Sequence
MSGREGGKKK PLKQPKKQAK EMDEEDKAFK QKQKEEQKKL EELKAKAAGK GPLATGGIKK 60
SGKK 64 
Gene Ontology
  
Interpro
 IPR015157; TMA7. 
Pfam
 PF09072; TMA7 
SMART
  
PROSITE
  
PRINTS