Tag | Content |
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CPLM ID | CPLM-013554 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Transcription initiation factor TFIID subunit 9 |
Protein Synonyms/Alias | RNA polymerase II TBP-associated factor subunit G; Transcription initiation factor TFIID 31 kDa subunit; TAFII-31; TAFII31; Transcription initiation factor TFIID 32 kDa subunit; TAFII-32; TAFII32 |
Gene Name | Taf9 |
Gene Synonyms/Alias | Taf2g; Tafii31 |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
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5 | ***MESGKMASPKSM | acetylation | [1] | 244 | NESANALKRKREEED | acetylation | [1] |
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Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Essential for cell viability. TAF9 and TAF9B are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes. May have a role in gene regulation associated with apoptosis. TAFs are components of the transcription factor IID (TFIID) complex, the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. TFIID or TFTC are essential for the regulation of RNA polymerase II-mediated transcription (By similarity). |
Sequence Annotation | MOD_RES 1 1 N-acetylmethionine (By similarity). MOD_RES 5 5 N6-acetyllysine (By similarity). MOD_RES 149 149 Phosphoserine (By similarity). MOD_RES 158 158 Phosphoserine (By similarity). MOD_RES 159 159 Phosphothreonine (By similarity). MOD_RES 161 161 Phosphothreonine (By similarity). MOD_RES 178 178 Phosphothreonine (By similarity). MOD_RES 181 181 Phosphoserine (By similarity). |
Keyword | Acetylation; Alternative splicing; Complete proteome; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 264 AA |
Protein Sequence | MESGKMASPK SMPKDAQMMA QILKDMGITE YEPRVINQML EFAFRYVTTI LDDAKIYSSH 60 AKKPTVDADD VRLAIQCRAD QSFTSPPPRD FLLDIARQRN QTPLPLIKPY SGPRLPPDRY 120 CLTAPNYRLK SLQKKAPTPA GRITVPRLSV GSVSSRPSTP TLGTPTPQAM SVSTKVGTPM 180 SLTGQRFTVQ MPASQSPAVK ASIPATPAVQ NVLINPSLIG SKNILITTNM VSQNTANESA 240 NALKRKREEE DDDDDDDDDD YDNL 264 |
Gene Ontology | GO:0071339; C:MLL1 complex; ISS:UniProtKB. GO:0006352; P:DNA-dependent transcription, initiation; IEA:InterPro. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. |
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