CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043102
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 PCK2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
120DVARVESKTVIVTPSubiquitination[1, 2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 509 AA 
Protein Sequence
MGGGASKSGA EEWTQSSNGR DGLNWHGLSP LGWPSCRSIQ TLRVLSGDLG QLPTGIRDFV 60
EHSARLCQPE GIHICDGTEA ENTATLTLLE QQGLIRKLPK YNNCWLARTD PKDVARVESK 120
TVIVTPSQRD TVQLPPGGAR GQLGNWMSPA DFQRAVDERF PGCMQGRTMY VLPFSMGPVG 180
SPLSRIGVQL TDSAYVVASM RIMTRLGTPV LQALGDGDFV KCLHSVGQPL TGQGEPVSQW 240
PCNPEKTLIG HVPDQREIIS FGSGYGGNSL LGKKCFALRI ASRLARDEGW LAEHMLILGI 300
TSPAGKKRYV AAAFPSACGK TNLAMMRPAL PGWKVECVGD DIAWMRFDSE GRLRAINPEN 360
GFFGVAPGTS ATTNPNAMAT IQSNTIFTNV AETSDGGVYW EGIDQPLPPG VTVTSWLGKP 420
WKPGDKEPCA HPNSRFCAPA RQCPIMDPAW EAPEGVPIDA IIFGGRRPKG VPLVYEAFNW 480
RHGVFVGSAM RSESTAAAEH KGLLGTGGS 509 
Gene Ontology
 GO:0005525; F:GTP binding; IEA:InterPro.
 GO:0004613; F:phosphoenolpyruvate carboxykinase (GTP) activity; IEA:InterPro.
 GO:0006094; P:gluconeogenesis; IEA:InterPro. 
Interpro
 IPR018091; PEP_carboxykin_GTP_CS.
 IPR013035; PEP_carboxykinase_C.
 IPR008209; PEP_carboxykinase_GTP.
 IPR008210; PEP_carboxykinase_N. 
Pfam
 PF00821; PEPCK 
SMART
  
PROSITE
 PS00505; PEPCK_GTP 
PRINTS