| Tag | Content |
|---|
| CPLM ID | CPLM-013564 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Terminal uridylyltransferase 7 |
Protein Synonyms/Alias | TUTase 7; Zinc finger CCHC domain-containing protein 6 |
Gene Name | Zcchc6 |
Gene Synonyms/Alias | Kiaa1711; Tut7 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 602 | IEDPYSVKRNVARTL | ubiquitination | [1] | | 1037 | KQDFPGTKLSLFGSS | ubiquitination | [1] | | 1045 | LSLFGSSKNGFGFKQ | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Uridylyltransferase that mediates the terminal uridylation of some specific RNAs. Not involved in uridylation of precursor let-7 (pre-let-7) miRNA. Does not play a role in replication-dependent histone mRNA degradation (By similarity). |
Sequence Annotation | DOMAIN 551 600 PAP-associated 1.
DOMAIN 1230 1282 PAP-associated 2.
ZN_FING 959 976 CCHC-type 1.
ZN_FING 1341 1358 CCHC-type 2.
ZN_FING 1447 1464 CCHC-type 3.
METAL 1054 1054 Magnesium or manganese; catalytic (By
METAL 1056 1056 Magnesium or manganese; catalytic (By
MOD_RES 64 64 Phosphothreonine (By similarity).
MOD_RES 132 132 Phosphoserine.
MOD_RES 172 172 Phosphoserine (By similarity). |
Keyword | Complete proteome; Magnesium; Manganese; Metal-binding; Nucleotidyltransferase; Phosphoprotein; Reference proteome; Repeat; Transferase; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1491 AA |
Protein Sequence | MGDTAKPYFV KRTKDRGIID DDDFRRGHPQ QDYLIMDDYA KGHSSKMEKG LPKKKISPGN 60
YGNTPRKGLY GVSSNPYAFK NPIYSQPAWM NDNHKDQNKK WLSDELAGNA DSWREFKPGP 120
RIPVISRSRK ESFQESDDAY RWQEGRGCRA VRRLFQKDLS SLEAMSEMEA GSPENKKQRS 180
RPRKPRRTRT EDSEQDGDLD GPVIDESVLS TKELLGLQQA EERLKRDCID RLKRRPRNCP 240
TAKYTCKLCD ALIDSIPFAH KHIKEKRHKK NLKEKQEEEL LTTLPPPAPS QIHAVGSAID 300
RVVQEFGLHS ENLDQRLEIK RVMESVFRHK LPDCSLRLYG SSCSRLGFRD SDVNIDVQFP 360
AVMSQPDVLL LVQECLKNSD SFIDVDADFH ARVPVVVCRD KQSGLLCKVS AGNENAWLTT 420
KHLTALGKLE PRLVPLVIAF RYWAKLCSID RPEEGGLPPY VFALMAVFFL QQRKEPLLPV 480
YLGSWIEEFS LNKLGNFSLK DVEKDSVVWE YTDNSTGDTS SAKEEAPKET AAKKGQVPLT 540
FNIKHQPSVP VGQLWVELLR FYALEFNLAD LVISIRVKEL ISRESKDWPK KRIAIEDPYS 600
VKRNVARTLN NQPVFEYILH CLRTTYKYFA LPHKVTKPNL TKPPSPVTCV SDPYREAKNG 660
GPEPQATNID KLGNAAVAQD PGVQTSGDCR AQLVTLKNTT EEVGSPAKEK TGGVHIPAHQ 720
ESSGCVQAEV SCEGLEDATA ELPETGSDNE EVRRKTKHPL STDDQGLSSS KHPELQNCGS 780
LCGLQADNTL ELVAEECNSC ASLDNKAEVN EERIEGAEEL EEAAALSCFS PSVQSRTSAA 840
MHFDDEEEEE EEEEEEEPRL SINLTEDEEG VANEHQVDSR YAGSGEEDAL SEEDDLAEPA 900
KGEDTGECGE NVGGTLLIDL NRITLKEESF PEEDLPGDQS EFFYEFRKLT FTKGKSPTVV 960
CSLCKREGHL KKDCPEDFKR VQLEPLPPLT PKFSNILDQV CVQCYKDFSP TIVEDQAREH 1020
IRQNLESFIK QDFPGTKLSL FGSSKNGFGF KQSDLDVCMT INGHETAEGL DCVRTIEELA 1080
RVLRKHSGLR NILPITTAKV PIVKFFHLRS GLEVDISLYN TLALHNTRLL SAYSAIDPRV 1140
KYLCYTMKVF TKMCDIGDAS RGSLSSYAYT LMVLYFLQQR SPPVIPVLQE IYKGEKKPEI 1200
LVDGWNIYFF DQINELPTCW PEYGKNTEPV GQLWLGLLRF YTEEFDFKEH VISIRRKSLL 1260
TTFKKQWTSK YIVIEDPFDL NHNLGAGLSR KMTNFIMKAF INGRRVFGIP VKGFPKDNPS 1320
KLAYFFDPDV LTEGELAPND RCCRICGKIG HFMKDCPMRR KVRRRRDQED TPNQRYSESK 1380
EKRSKEDKEI QNKYTEKEVS TKEDKLTPCA AAKAKPVRAA VDLGREKLLR TPTEKWKRQD 1440
DRDSREKRCF ICGREGHIKK ECPQFKGSPG SLSSKYMTQG RASVKRTQQE S 1491 |
Gene Ontology | GO:0003676; F:nucleic acid binding; IEA:InterPro. GO:0050265; F:RNA uridylyltransferase activity; ISS:UniProtKB. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0031123; P:RNA 3'-end processing; ISS:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |