CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026924
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MKIAA0334 protein 
Protein Synonyms/Alias
  
Gene Name
 Clock 
Gene Synonyms/Alias
 mKIAA0334 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
188SLTPEYLKSKNQLEFubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 DNA-binding; Nucleus; Repeat; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 857 AA 
Protein Sequence
CVMVFTVSCS KMSSIVDRDD SSIFDGLVEE DDKDKAKRVS RNKSEKKRRD QFNVLIKELG 60
SMLPGNARKM DKSTVLQKSI DFLRKHKETT AQSDASEIRQ DWKPTFLSNE EFTQLMLEAL 120
DGFFLAIMTD GSIIYVSESV TSLLEHLPSD LVDQSIFNFI PEGEHSEVYK ILSTHLLESD 180
SLTPEYLKSK NQLEFCCHML RGTIDPKEPS TYEYVRFIGN FKSLTSVSTS THNGFEGTIQ 240
RTHRPSYEDR VCFVATVRLA TPQFIKEMCT VEEPNEEFTS RHSLEWKFLF LDHRAPPIIG 300
YLPFEVLGTS GYDYYHVDDL ENLAKCHEHL MQYGKGKSCY YRFLTKGQQW IWLQTHYYIT 360
YHQWNSRPEF IVCTHTVVSY AEVRAERRRE LGIEESLPET AADKSQDSGS DNRINTVSLK 420
EALERFDHSP TPSASSRSSR KSSHTAVSDP SSTPTKIPTD TSTPPRQHLP AHEKMTQRRS 480
SFSSQSINSQ SVGPSLTQPA MSQAANLPIP QGMSQFQFSA QLGAMQHLKD QLEQRTRMIE 540
ANIHRQQEEL RKIQEQLQMV HGQGLQMFLQ QSNPGLNFGS VQLSSGNSNI QQLTPVNMQG 600
QVVPANQVQS GHISTGQHMI QQQTLQSTST QQSQQSVMSG HSQQTSLPSQ TPSTLTAPLY 660
NTMVISQPAA GSMVQIPSSM PQNSTQSATV TTFTQDRQIR FSQGQQLVTK LVTAPVACGA 720
VMVPSTMLMG QVVTAYPTFA TQQQQAQTLS VTQQQQQQQQ QPPQQQQQQQ QSSQEQQLPS 780
VQQPAQAQLG QPPQQFLQTS RLLHGNPSTQ LILSAAFPLQ QSTFPPSHHQ QHQPQQQQQL 840
PRHRTDSLTD PSKVQPQ 857 
Gene Ontology
 GO:0005694; C:chromosome; IEA:Compara.
 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0005667; C:transcription factor complex; IDA:MGI.
 GO:0070888; F:E-box binding; IEA:Compara.
 GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IEA:Compara.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
 GO:0004871; F:signal transducer activity; IEA:InterPro.
 GO:0008134; F:transcription factor binding; ISA:MGI.
 GO:0071479; P:cellular response to ionizing radiation; IEA:Compara.
 GO:0007623; P:circadian rhythm; IDA:MGI.
 GO:0000077; P:DNA damage checkpoint; IEA:Compara.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR011598; bHLH_dom.
 IPR001067; Nuc_translocat.
 IPR001610; PAC.
 IPR000014; PAS.
 IPR013767; PAS_fold.
 IPR013655; PAS_fold_3. 
Pfam
 PF00010; HLH
 PF00989; PAS
 PF08447; PAS_3 
SMART
 SM00353; HLH
 SM00086; PAC
 SM00091; PAS 
PROSITE
 PS50888; BHLH
 PS50112; PAS 
PRINTS
 PR00785; NCTRNSLOCATR.