CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028368
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Lethal (2) 44DEa, isoform D 
Protein Synonyms/Alias
  
Gene Name
 Acsl 
Gene Synonyms/Alias
 l(2)44DEa; CG8732; Dmel_CG8732 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
136NLGDYKWKTFTEAERacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Ligase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 717 AA 
Protein Sequence
MKYNSLSYCV MDSFWVQSAI GAIKAIAFVY DIITLPVYLV LQKPWKRRQD SRRVKAKIVR 60
NDDNELTYRT TDPPRDVHVK MLQENIDTLE KVFNYVAKTY TSKRCLGTRQ ILSEEDEVQQ 120
NGRVFKKYNL GDYKWKTFTE AERTAANFGR GLRELGQKPR ENIVIFAETR AEWMIAAHGC 180
FKQAMPIVTV YATLGDDGVA HCITETEVTT VITSHDLLPK FKTLLDKCPL VKTIIYIEDQ 240
LQKTETTGFK EGVKILPFNQ VVKTGQDSKF EHVPPKGDDI AIIMYTSGST GTPKGVLLSH 300
KNCIATMKGF VDMVPIYPDD VLIGFLPLAH VFELVAESVC LMTGVPIGYS TPLTLIDTSS 360
KIKRGCKGDA TVLKPTCMTS VPLILDRISK GINDKVNSGS AFKKSLFKFL YQYKVKWVQR 420
GYKTPLIDKL VFKKVAKLMG GKVRIIMSGG APLSADTHEQ IKTCLCLELI QGYGLTETTS 480
GATVMDYRDM TYGRTGGPLT VCDIRLVNWE EGNYRVTNKP YPQGEVLIGG ECVSQGYYKL 540
PGKTNEDFFE EDGQRWFKTG DIGEIQADGV LKIIDRKKDL VKLQAGEYVS LGKVESELKT 600
CGIIENICVY GDPTKQYTVA LVVPNQNHLE ELAQKHGLGD KSFEELCSSP IIEKAILKEI 660
AEHARKCKLQ KYEVPAAITL CKEVWSPDMG LVTAAFKLKR KDIQDRYQHD INRMYAS 717 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; IDA:FlyBase.
 GO:0005811; C:lipid particle; IDA:FlyBase.
 GO:0004467; F:long-chain fatty acid-CoA ligase activity; IEA:EC.
 GO:0007411; P:axon guidance; IMP:FlyBase.
 GO:0001676; P:long-chain fatty acid metabolic process; IEA:GOC.
 GO:0010890; P:positive regulation of sequestering of triglyceride; IMP:FlyBase.
 GO:0035282; P:segmentation; IMP:FlyBase.
 GO:0007268; P:synaptic transmission; IMP:FlyBase. 
Interpro
 IPR020845; AMP-binding_CS.
 IPR000873; AMP-dep_Synth/Lig. 
Pfam
 PF00501; AMP-binding 
SMART
  
PROSITE
 PS00455; AMP_BINDING 
PRINTS