UniProt Accession

 F6R105_MOUSE; F6R105 

Genbank Protein ID

 AC156608 

Genbank Nucleotide ID

  

Protein Name

 Integrin beta-1 

Protein Synonyms/Alias

  

Gene Name

 Itgb1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
85	EKEKMNAKWDTQENP	ubiquitination	[1]
95	TQENPIYKSPINNFK	ubiquitination	[1]
102	KSPINNFKNPNYGRK	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 112 AA 

Protein Sequence

Gene Ontology

 GO:0009897; C:external side of plasma membrane; IDA:MGI.
 GO:0008305; C:integrin complex; IEA:InterPro.
 GO:0014704; C:intercalated disc; IDA:MGI.
 GO:0031594; C:neuromuscular junction; IDA:MGI.
 GO:0042383; C:sarcolemma; IDA:MGI.
 GO:0004872; F:receptor activity; IEA:InterPro.
 GO:0055007; P:cardiac muscle cell differentiation; IMP:MGI.
 GO:0001708; P:cell fate specification; IMP:MGI.
 GO:0002042; P:cell migration involved in sprouting angiogenesis; IMP:MGI.
 GO:0007160; P:cell-matrix adhesion; IGI:MGI.
 GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:MGI.
 GO:0008354; P:germ cell migration; IMP:MGI.
 GO:0001701; P:in utero embryonic development; IMP:MGI.
 GO:0007229; P:integrin-mediated signaling pathway; IEA:InterPro.
 GO:0045596; P:negative regulation of cell differentiation; IMP:MGI.
 GO:0031175; P:neuron projection development; IMP:MGI.
 GO:0008284; P:positive regulation of cell proliferation; IMP:MGI.
 GO:0051726; P:regulation of cell cycle; IMP:MGI.
 GO:0045214; P:sarcomere organization; IMP:MGI. 

Interpro

 IPR027071; Integrin_beta-1.
 IPR015812; Integrin_bsu.
 IPR014836; Integrin_bsu_cyt_dom.
 IPR012896; Integrin_bsu_tail. 

Pfam

 PF08725; Integrin_b_cyt
 PF07965; Integrin_B_tail 

SMART

  

PROSITE

  

PRINTS

 PR01186; INTEGRINB.