CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030950
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Syntaxin 5A, isoform CRA_c 
Protein Synonyms/Alias
 Syntaxin-5; cDNA FLJ57518, highly similar to Syntaxin-5 
Gene Name
 STX5 
Gene Synonyms/Alias
 STX5A; hCG_1734926 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
7*MAKRIGKDLSNTFAubiquitination[1]
18NTFAKLEKLTILAKRubiquitination[1]
32RKSLFDDKAVEIEELubiquitination[1]
52QDINSLNKQIAQLQDubiquitination[1, 2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
  
Keyword
 Coiled coil; Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 259 AA 
Protein Sequence
MAKRIGKDLS NTFAKLEKLT ILAKRKSLFD DKAVEIEELT YIIKQDINSL NKQIAQLQDF 60
VRAKGSQSGR HLQTHSNTIV VSLQSKLASM SNDFKSVLEV RTENLKQQRS RREQFSRAPV 120
SALPLAPNHL GGGAVVLGAE SHASKDVAID MMDSRTSQQL QLIDEQDSYI QSRADTMQNI 180
ESTIVELGSI FQQLAHMVKE QEETIQRIDE NVLGAQLDVE AAHSEILKYF QSVTSNRWLM 240
VKIFLILIVF FIIFVVFLA 259 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; IEA:Compara.
 GO:0005794; C:Golgi apparatus; IDA:HPA.
 GO:0000139; C:Golgi membrane; IEA:Compara.
 GO:0005634; C:nucleus; IDA:HPA.
 GO:0031201; C:SNARE complex; IEA:Compara.
 GO:0006888; P:ER to Golgi vesicle-mediated transport; IEA:Compara.
 GO:0006886; P:intracellular protein transport; IEA:InterPro.
 GO:0048280; P:vesicle fusion with Golgi apparatus; IEA:Compara. 
Interpro
 IPR006012; Syntaxin/epimorphin_CS.
 IPR006011; Syntaxin_N.
 IPR010989; t-SNARE.
 IPR000727; T_SNARE_dom. 
Pfam
 PF05739; SNARE
 PF00804; Syntaxin 
SMART
 SM00397; t_SNARE 
PROSITE
 PS00914; SYNTAXIN
 PS50192; T_SNARE 
PRINTS