CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039929
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein wntless homolog 
Protein Synonyms/Alias
  
Gene Name
 WLS 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
410VFRNISGKQSSLPAMubiquitination[1, 2, 3]
419SSLPAMSKVRRLHYEubiquitination[1, 2, 3, 4]
512NGMQLPCKSREDCALubiquitination[2]
533QELFSASKYSFINDNubiquitination[3]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [4] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 545 AA 
Protein Sequence
MAGAIIENMS TKKLCIVGGI LLVFQIIAFL VGGLIAPGPT TAVSYMSVKC VDARKNHHKT 60
KWFVPWGPNH CDKIRDIEEA IPREIEANDI VFSVHIPLPH MEMSPWFQFM LFILQLDIAF 120
KLNNQIRENA EVSMDVSLAY RDDAFAEWTE MAHERVPRKL KCTFTSPKTP EHEGRYYECD 180
VLPFMEIGSV AHKFYLLNIR LPVNEKKKIN VGIGEIKDIR LVGIHQNGGF TKVWFAMKTF 240
LTPSIFIIMV WYWRRITMMS RPPVLLEKVI FALGISMTFI NIPVEWFSIG FDWTWMLLFG 300
DIRQGIFYAM LLSFWIIFCG EHMMDQHERN HIAGYWKQVG PIAVGSFCLF IFDMCERGVQ 360
LTNPFYSIWT TDIGTELAMA FIIVAGICLC LYFLFLCFMV FQVFRNISGK QSSLPAMSKV 420
RRLHYEGLIF RFKFLMLITL ACAAMTVIFF IVSQVTEGHW KWGGVTVQVN SAFFTGIYGM 480
WNLYVFALMF LYAPSHKNYG EDQSNGMQLP CKSREDCALF VSELYQELFS ASKYSFINDN 540
AASGI 545 
Gene Ontology
 GO:0016055; P:Wnt receptor signaling pathway; IEA:InterPro. 
Interpro
 IPR009551; Wntless. 
Pfam
  
SMART
  
PROSITE
  
PRINTS