UniProt Accession

 LPTA_ECOLI; P0ADV1; P38685; Q2M912 

Genbank Protein ID

 U12684; U18997; U00096; AP009048 

Genbank Nucleotide ID

 AAB60161.1; AAA58002.1; AAC76232.1; BAE77244.1 

Protein Name

 Lipopolysaccharide export system protein LptA 

Protein Synonyms/Alias

  

Gene Name

 lptA 

Gene Synonyms/Alias

 yhbN; b3200; JW3167 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
71	TIKINADKVVVTRPG	acetylation	[1]
83	RPGGEQGKEVIDGYG	acetylation	[1]
103	YQMQDNGKPVEGHAS	acetylation	[1]
140	DSNIKGDKITYLVKE	acetylation	[1]
172	VPSQLQDKNNKGQTP	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. May act as a chaperone that facilitates LPS transfer across the aquaeous environment of the periplasm. Interacts specifically with the lipid A domain of LPS. 

Sequence Annotation

  

Keyword

 3D-structure; Chaperone; Complete proteome; Direct protein sequencing; Periplasm; Reference proteome; Signal; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 185 AA 

Protein Sequence

Gene Ontology

 GO:0009279; C:cell outer membrane; IDA:EcoCyc.
 GO:0030288; C:outer membrane-bounded periplasmic space; IDA:EcoCyc.
 GO:0017089; F:glycolipid transporter activity; IMP:EcoCyc.
 GO:0001530; F:lipopolysaccharide binding; IEA:InterPro.
 GO:0015920; P:lipopolysaccharide transport; IMP:EcoCyc. 

Interpro

 IPR014340; LipoPS_assembly_LptA.
 IPR005653; OstA-like_N. 

Pfam

 PF03968; OstA 

SMART

  

PROSITE

  

PRINTS