UniProt Accession

 Q8MPF6_TOXGO; Q8MPF6; B6KHU7; B9PRL3; B9QCJ7 

Genbank Protein ID

 AJ496759; DS984732; EQ967481; EQ970684 

Genbank Nucleotide ID

 CAD43147.1; EEB00280.1; EEE23342.1; EEE31526.1 

Protein Name

 Initiation factor 5A, putative 

Protein Synonyms/Alias

 Putative translation initiation factor 5A2; Translation initiation factor 5A2; Translation initiation factor eIF-5A, putative 

Gene Name

 eIF5A2 

Gene Synonyms/Alias

 TGGT1_103180; TGME49_051810; TGVEG_000540 

Created Date

 July 27, 2013 

Organism

 Toxoplasma gondii 

NCBI Taxa ID

 5811 

Lysine Modification

Position	Peptide	Type	References
36	KNGFVMLKGNPCKVV	acetylation	[1]
41	MLKGNPCKVVDYSTS	acetylation	[1, 2]

Reference

 [1] Lysine acetylation is widespread on proteins of diverse function and localization in the protozoan parasite Toxoplasma gondii.
 Jeffers V, Sullivan WJ Jr.
 Eukaryot Cell. 2012 Jun;11(6):735-42. [PMID: 22544907]
 [2] Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii.
 Xue B, Jeffers V, Sullivan WJ, Uversky VN.
 Mol Biosyst. 2013 Apr 5;9(4):645-57. [PMID: 23403842] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Initiation factor; Protein biosynthesis; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 161 AA 

Protein Sequence

Gene Ontology

 GO:0043022; F:ribosome binding; IEA:InterPro.
 GO:0003746; F:translation elongation factor activity; IEA:InterPro.
 GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
 GO:0008612; P:peptidyl-lysine modification to hypusine; IEA:InterPro.
 GO:0045901; P:positive regulation of translational elongation; IEA:InterPro.
 GO:0045905; P:positive regulation of translational termination; IEA:InterPro.
 GO:0006452; P:translational frameshifting; IEA:InterPro. 

Interpro

 IPR012340; NA-bd_OB-fold.
 IPR014722; Rib_L2_dom2.
 IPR019769; Trans_elong_IF5A_hypusine_site.
 IPR001884; Transl_elong_IF5A.
 IPR020189; Transl_elong_IF5A_C.
 IPR008991; Translation_prot_SH3-like. 

Pfam

 PF01287; eIF-5a 

SMART

  

PROSITE

 PS00302; IF5A_HYPUSINE 

PRINTS