CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039927
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Peroxisomal membrane protein PEX14 
Protein Synonyms/Alias
  
Gene Name
 PEX14 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
149SQNINELKSEINSLKubiquitination[1, 2]
156KSEINSLKGLLLNRRubiquitination[1, 2, 3]
299QINEQVEKLRRPEGAubiquitination[1, 3]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 313 AA 
Protein Sequence
MAFQQSGTAA DEPSSLGPAT QVVPVQPPHL ISQPYSPAGS RWRDYGALAI IMAGIAFGFH 60
QLYKKYLLPL ILGGREDRKQ LERMEAGLSE LSGSVAQTVT QLQTTLASVQ ELLIQQQQKI 120
QELAHELAAA KATTSTNWIL ESQNINELKS EINSLKGLLL NRRQFPPSPS APKIPSWQIP 180
VKSPSPSSPA AVNHHSSSDI SPVSNESTSS SPGKEGHSPE GSTVTYHLLG PQEEGEGVVD 240
VKGQVRMEVQ GEEEKREDKE DEEDEEDDDV SHVDEEDCLG VQREDRRGGD GQINEQVEKL 300
RRPEGASNES ERD 313 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:Compara.
 GO:0005778; C:peroxisomal membrane; IEA:Compara.
 GO:0043234; C:protein complex; IEA:Compara.
 GO:0003714; F:transcription corepressor activity; IEA:InterPro.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; IEA:InterPro.
 GO:0016558; P:protein import into peroxisome matrix; IEA:InterPro. 
Interpro
 IPR025655; PEX14. 
Pfam
  
SMART
  
PROSITE
  
PRINTS