CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026805
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Translation initiation factor IF-3 
Protein Synonyms/Alias
  
Gene Name
 infC 
Gene Synonyms/Alias
 RPA0040 
Created Date
 July 27, 2013 
Organism
 Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) 
NCBI Taxa ID
 258594 
Lysine Modification
Position
Peptide
Type
References
26RAPPPVAKDGPRTNDacetylation[1]
173NDVAEIAKVEQDPRFacetylation[1]
Reference
 [1] System-wide studies of N-lysine acetylation in Rhodopseudomonas palustris reveal substrate specificity of protein acetyltransferases.
 Crosby HA, Pelletier DA, Hurst GB, Escalante-Semerena JC.
 J Biol Chem. 2012 May 4;287(19):15590-601. [PMID: 22416131
Functional Description
 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Cytoplasm; Initiation factor; Protein biosynthesis. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 192 AA 
Protein Sequence
MFAVNVHKCG EAPIRRPNRA PPPVAKDGPR TNDEIRNFEI QLIDQTGVNQ GKVETIVAIK 60
MAMDAGMDLV EISPTSSPPV CKIMDYGKYK YSAQKKAAEA RKKQKIVEIK EIKLRPMIDD 120
HDYEVKMKAM QRFFEEGDKV KITLRYRGRE MAHQEIGTKL LEKVKNDVAE IAKVEQDPRF 180
EGRQVVMVLA PR 192 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0003743; F:translation initiation factor activity; IEA:HAMAP. 
Interpro
 IPR001288; Translation_initiation_fac_3.
 IPR019815; Translation_initiation_fac_3_C.
 IPR019814; Translation_initiation_fac_3_N. 
Pfam
 PF00707; IF3_C
 PF05198; IF3_N 
SMART
  
PROSITE
  
PRINTS