CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034450
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Serine/threonine-protein kinase BRSK1 
Protein Synonyms/Alias
  
Gene Name
 Brsk1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
92ENLLLDEKNNIRIADubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 703 AA 
Protein Sequence
MKVEREIAIL KLIEHPHVLK LHDVYENKKY LYLVLEHVSG GELFDYLVKK GRLTPKEARK 60
FFRQIVSALD FCHSYSICHR DLKPENLLLD EKNNIRIADF GMASLQVGDS LLETSCGSPH 120
YACPEVIKGE KYDGRRADMW SCGVILFALL VGALPFDDDN LRQLLEKVKR GVFHMPHFIP 180
PDCQSLLRGM IEVEPEKRLS LEQIQKHPWY LGGKHEPDPC LEPAPGRRVA MRSLPSNGEL 240
DPDVLESMAS LGCFRDRERL HRELRSEEEN QEKMIYYLLL DRKERYPSCE DQDLPPRNDV 300
DPPRKRVDSP MLSRHGKRRP ERKSMEVLSI TDAGSGGSPV PTRRALEMAQ HSQRSRSVSG 360
ASTGLSSSPL SSPRSPVFSF SPEPGAGDEA RGGGSPTSKT QTLPSRGPRG GGAGEQPPPP 420
SARSTPLPGP PGSPRSSGGT PLHSPLHTPR ASPTGTPGTT PPPSPGGGVG GAAWRSRLNS 480
IRNSFLGSPR FHRRKMQVPT AEEMSSLTPE SSPELAKRSW FGNFISLDKE EQIFLVLKDK 540
PLSSIKADIV HAFLSIPSLS HSVLSQTSFR AEYKASGGPS VFQKPVRFQV DISSSEGPEP 600
SPRRDGSSGG GIYSVTFTLI SGPSRRFKRV VETIQAQLLS THDQPSVQAL ADEKNGAQTR 660
PAGTPPRSLQ PPPGRSDPDL SSSPRRGPPK DKKLLATNGT PLP 703 
Gene Ontology
 GO:0030054; C:cell junction; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0008021; C:synaptic vesicle; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0000287; F:magnesium ion binding; IEA:Compara.
 GO:0004674; F:protein serine/threonine kinase activity; IEA:Compara.
 GO:0030010; P:establishment of cell polarity; IGI:MGI.
 GO:0031572; P:G2 DNA damage checkpoint; IEA:Compara.
 GO:0048812; P:neuron projection morphogenesis; IGI:MGI.
 GO:0007269; P:neurotransmitter secretion; IEA:Compara.
 GO:0009411; P:response to UV; IEA:Compara. 
Interpro
 IPR011009; Kinase-like_dom.
 IPR000719; Prot_kinase_cat_dom.
 IPR002290; Ser/Thr_dual-sp_kinase_dom.
 IPR008271; Ser/Thr_kinase_AS.
 IPR015940; UBA/transl_elong_EF1B_N_euk. 
Pfam
 PF00069; Pkinase 
SMART
 SM00220; S_TKc 
PROSITE
 PS50011; PROTEIN_KINASE_DOM
 PS00108; PROTEIN_KINASE_ST
 PS50030; UBA 
PRINTS