| Tag | Content |
|---|
| CPLM ID | CPLM-015531 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Rho GTPase-activating protein 26 |
Protein Synonyms/Alias | Rho-type GTPase-activating protein 26 |
Gene Name | Arhgap26 |
Gene Synonyms/Alias | Kiaa0621 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 454 | KTVTSALKTYLRMLP | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | GTPase-activating protein for RHOA and CDC42 (By similarity). |
Sequence Annotation | DOMAIN 265 369 PH.
DOMAIN 383 568 Rho-GAP.
DOMAIN 756 814 SH3. |
Keyword | Cell junction; Complete proteome; Cytoplasm; Cytoskeleton; GTPase activation; Reference proteome; SH3 domain. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 814 AA |
Protein Sequence | MGLPALEFSD CCLDSPHFRE TLKSHEAELD KTNKFIKELI KDGKSLISAL KNLSSAKRKF 60
ADSLNEFKFQ CIGDAETDDE MCIARSLQEF AAVLRNLEDE RSRMIENASE VLITPLEKFR 120
KEQIGAAREA KKKYDKETEK YCGTLEKHLN LSSKKKESQL QEADSQVDLV RQHFYEVSLE 180
YVFKVQEVQE RKMFEFVEPL LAFLQGLFTF YHHGYELAKD FGDFKTQLTI SIQNTRNRFE 240
GTRSEVESLM KKMKENPLEH KTISPYTMEG YLYVQEKRHF GTSWVKHYCT YQRDSKQITM 300
VPFDQKSGGK GGEDESVTLK SCTRRKTDSI EKRFCFDVEA VDRPGVITMQ ALSEEDRRLW 360
MEAMDGREPV YNSNRDSQSE GTAQLDSIGF SIIRKCIHAV ETRGINEQGL YRIVGVNSRV 420
QKLLSVLMDP KAASETETDI CAEWEIKTVT SALKTYLRML PGPLMMYQFQ RSFIKAAKLE 480
NQETRVSEIH SLVHRLPEKN RQMLQLLMNH LANVANNHKQ NLMTVANLGV VFGPTLLRPQ 540
EETVAAIMDI KFQNIVIEIL IENHEKIFNT VPDVPLTNAQ LHLSRKKSSD SKPPSCSKRP 600
LTLFHAVPST EKQEQRNSII NSSLESVSSS ANSILNSSSS LQPNLNSSDS NLDVVKPSRP 660
SSLPPNPSPT SPLSPSWPMF SAPSSPMPTS STSSDSSPIR SVAGFVWFSV AAVVLSLAWS 720
SLHAVFSLLV NFVPCHPNLH LLFDRPEEAV REDSSTPFRK AKALYACQAE HDSELSFTAG 780
TVFDNVHPSQ EPGWLEGTLN GKTGLIPENY VEFL 814 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW. GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. GO:0005543; F:phospholipid binding; IEA:InterPro. GO:0046847; P:filopodium assembly; IEA:InterPro. GO:0043547; P:positive regulation of GTPase activity; IEA:GOC. GO:0007165; P:signal transduction; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |