CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030629
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Phospholipase DDHD2 
Protein Synonyms/Alias
 cDNA FLJ45096 fis, clone BRAWH3030910, highly similar to Homo sapiens DDHD domain containing 2 (DDHD2), mRNA 
Gene Name
 DDHD2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
206TRMSMDLKNNLLGSLubiquitination[1, 2]
218GSLRMAWKSFTRAPYubiquitination[2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 330 AA 
Protein Sequence
MDQGDTPTLE EDLKKLQLSE FFDIFEKEKV DKEALALCTD RDLQEIGIPL GPRKKILNYF 60
STRKNSMGIK RPAPQPASGA NIPKESEFCS SSNTRNGDYL DVGIGQVSVK YPRLIYKPEI 120
FFAFGSPIGM FLTVRGLKRI DPNYRFPTCK GFFNIYHPFD PVAYRIEPMV VPGVEFEPML 180
IPHHKGRKRM HLELREGLTR MSMDLKNNLL GSLRMAWKSF TRAPYPALQA SETPEETEAE 240
PESTSEKPSD VNTEETSVAV KEEVLPINVG MLNGGQRIDY VLQEKPIESF NEYLFALQSH 300
LCYWESEDTV LLVLKEIYQT QGIFLDQPLQ 330 
Gene Ontology
 GO:0005813; C:centrosome; IDA:HPA.
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0046872; F:metal ion binding; IEA:InterPro. 
Interpro
 IPR004177; DDHD.
 IPR001660; SAM.
 IPR013761; SAM/pointed.
 IPR021129; SAM_type1. 
Pfam
 PF02862; DDHD
 PF00536; SAM_1 
SMART
 SM00454; SAM 
PROSITE
 PS51043; DDHD 
PRINTS