CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041584
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Akr1b8 
Protein Synonyms/Alias
 RCG27994 
Gene Name
 Akr1b8 
Gene Synonyms/Alias
 rCG_27994 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
10TFVELSTKAKMPIVGacetylation[1]
125AGKELFPKDEQGNVLacetylation[1]
233PSLLQDPKIKEIAAKacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
 ACT_SITE 49 49 Proton donor (By similarity).  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 316 AA 
Protein Sequence
MATFVELSTK AKMPIVGLGT WKSTPNQVKE AVKAAIDAGY RHIDCAYAYC NENEVGEAIQ 60
EKIKEKAVRR EDLFIVSKLW PTCFEKKLLK EAFQKTLTDL KLDYLDLYLI HWPQGFQAGK 120
ELFPKDEQGN VLPSKTTFLE AWEGMEELVD QGLVKALGVS NFNHFQIERL LNKPGLKHKP 180
VTNQVECHPY LTQEKLIQYC HSKGIVVTAY SPLGSPDRPR AKPDDPSLLQ DPKIKEIAAK 240
HKKTTAQVLI RFHIQRNVVV IPKSVTPARI QENIQVFDFQ LSDQEMATIL SFNRNWRACL 300
LPETVNMEEF PYDAEY 316 
Gene Ontology
 GO:0016491; F:oxidoreductase activity; IEA:InterPro. 
Interpro
 IPR001395; Aldo/ket_red.
 IPR018170; Aldo/ket_reductase_CS.
 IPR020471; Aldo/keto_reductase_subgr.
 IPR023210; NADP_OxRdtase_dom. 
Pfam
 PF00248; Aldo_ket_red 
SMART
  
PROSITE
 PS00798; ALDOKETO_REDUCTASE_1
 PS00062; ALDOKETO_REDUCTASE_2
 PS00063; ALDOKETO_REDUCTASE_3 
PRINTS
 PR00069; ALDKETRDTASE.