CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031647
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Sash3 
Protein Synonyms/Alias
 Sash3 protein; Similar to RIKEN cDNA 1200013B08 (Predicted) 
Gene Name
 Sash3 
Gene Synonyms/Alias
 RGD1560293_predicted; rCG_53240 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
35FKDFAKSKPSSPVVSacetylation[1]
90TMNRKMGKMMVKALSacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 380 AA 
Protein Sequence
MLRRKPSNAS DKEPTQKKKL SLQRSSSFKD FAKSKPSSPV VSEKEFNLDD NIPEDDSGVL 60
TPEDSGKSGK KLGKKWRAVI SRTMNRKMGK MMVKALSEEM GDTLEEGSAS PTSPDCSLDS 120
PGPEKMALAF SEPEERELLA LSRQTSTGSE LCSPGPGSGS FIEESPAPQY TGPFCGRARV 180
HTDFTPSPYD HDSLKLQKGD VIQIIEKPPV GTWLGLLNGK LGSFKFIYVD VLPEEAVGPV 240
RPSRRQSKSK RPKPKTLHEL LERIGLEEHT STLLLNGYQT LEDFKELRET HLNELNIMDP 300
QHRAKLLTAA ELLLDYDTGS EEAEEGAESS QEPALHTVSE PKVDIPRDSG CFEGSESGRD 360
EAELTGTEEQ LQGLSLAGAP 380 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0048873; P:homeostasis of number of cells within a tissue; IEA:Compara.
 GO:0030890; P:positive regulation of B cell proliferation; IEA:Compara.
 GO:0043372; P:positive regulation of CD4-positive, alpha-beta T cell differentiation; IEA:Compara.
 GO:0002639; P:positive regulation of immunoglobulin production; IEA:Compara.
 GO:0032729; P:positive regulation of interferon-gamma production; IEA:Compara.
 GO:0032733; P:positive regulation of interleukin-10 production; IEA:Compara.
 GO:0032743; P:positive regulation of interleukin-2 production; IEA:Compara.
 GO:0032753; P:positive regulation of interleukin-4 production; IEA:Compara.
 GO:0046622; P:positive regulation of organ growth; IEA:Compara.
 GO:0002726; P:positive regulation of T cell cytokine production; IEA:Compara.
 GO:0042102; P:positive regulation of T cell proliferation; IEA:Compara.
 GO:0032760; P:positive regulation of tumor necrosis factor production; IEA:Compara. 
Interpro
 IPR021090; rSAM/SH3_domain-containing.
 IPR001660; SAM.
 IPR013761; SAM/pointed.
 IPR011510; SAM_2.
 IPR011511; SH3_2.
 IPR001452; SH3_domain. 
Pfam
 PF07647; SAM_2
 PF07653; SH3_2
 PF12485; SLY 
SMART
 SM00454; SAM
 SM00326; SH3 
PROSITE
 PS50105; SAM_DOMAIN 
PRINTS