CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036082
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Exocyst complex component 3 
Protein Synonyms/Alias
  
Gene Name
 EXOC3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
28QRPDQLDKVEQYRRRacetylation[1, 2, 3]
144ALLQAHRKLMDLECSubiquitination[4]
351LNTYTRYKDEAQLYKubiquitination[4]
Reference
 [1] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773]
 [2] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 462 AA 
Protein Sequence
MKETDREAVA TAVQRVAGML QRPDQLDKVE QYRRREARKK ASVEARLKAA IQSQLDGVRT 60
GLSQLHNALN DVKDIQQSLA DVSKDWRQSI NTIESLKDVK DAVVQHSQLA AAVENLKNIF 120
SVPEIVRETQ DLIEQGALLQ AHRKLMDLEC SRDGLMYEQY RMDSGNTRDM TLIHGYFGST 180
QGLSDELAKQ LWMVLQRSLV TVRRDPTLLV SVVRIIEREE KIDRRILDRK KQTGFVPPGR 240
PKNWKEKMFT ILERTVTTRI EGTQADTRES DKMWLVRHLE IIRKYVLDDL IVAKNLMVQC 300
FPPHYEIFKN LLNMYHQALS TRMQDLASED LEANEIVSLL TWVLNTYTRY KDEAQLYKEE 360
HLRNRQHPHC YVQYMIAIIN NCQTFKESIV SLKRKYLKNE VEEGVSPSQP SMDGILDAIA 420
KEGCSGLLEE VFLDLEVGLA LSSCRFLGRS PVLPHCPLGH RL 462 
Gene Ontology
 GO:0000145; C:exocyst; IEA:InterPro.
 GO:0006887; P:exocytosis; IEA:InterPro. 
Interpro
 IPR010326; Sec6. 
Pfam
 PF06046; Sec6 
SMART
  
PROSITE
  
PRINTS