CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011681
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Intermediate filament family orphan 1 
Protein Synonyms/Alias
 Tumor antigen HOM-TES-103 
Gene Name
 IFFO1 
Gene Synonyms/Alias
 IFFO 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
78GSNINVLKTLNLRFRubiquitination[1, 2]
103RRNRLLEKQLQQALEubiquitination[2]
113QQALEEGKQGRRGLGubiquitination[2]
247ALYNVLAKVKRERDEubiquitination[3]
293CQEELALKVEQLKAEubiquitination[2]
305KAELVVFKGLMSNNLubiquitination[2]
318NLSELDTKIQEKAMKubiquitination[2]
358DMIQMFQKKLVPSMGubiquitination[2]
359MIQMFQKKLVPSMGGubiquitination[2]
464DSLEKVIKDTESLFKubiquitination[2]
471KDTESLFKTREKEYQubiquitination[2]
492ELELATAKNDMNRHLubiquitination[2]
Reference
 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789
Functional Description
  
Sequence Annotation
  
Keyword
 Alternative splicing; Coiled coil; Complete proteome; Intermediate filament; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 559 AA 
Protein Sequence
MNPLFGPNLF LLQQEQQGLA GPLGDSLGGD HFAGGGDLPP APLSPAGPAA YSPPGPGPAP 60
PAAMALRNDL GSNINVLKTL NLRFRCFLAK VHELERRNRL LEKQLQQALE EGKQGRRGLG 120
RRDQAVQTGF VSPIRPLGLQ LGARPAAVCS PSARVLGSPA RSPAGPLAPS AASLSSSSTS 180
TSTTYSSSAR FMPGTIWSFS HARRLGPGLE PTLVQGPGLS WVHPDGVGVQ IDTITPEIRA 240
LYNVLAKVKR ERDEYKRRWE EEYTVRIQLQ DRVNELQEEA QEADACQEEL ALKVEQLKAE 300
LVVFKGLMSN NLSELDTKIQ EKAMKVDMDI CRRIDITAKL CDVAQQRNCE DMIQMFQKKL 360
VPSMGGRKRE RKAAVEEDTS LSESEGPRQP DGDEEESTAL SINEEMQRML NQLREYDFED 420
DCDSLTWEET EETLLLWEDF SGYAMAAAEA QGEQQEDSLE KVIKDTESLF KTREKEYQET 480
IDQIELELAT AKNDMNRHLH EYMEMCSMKR GLDVQMETCR RLITQSGDRK SPAFTAVPLS 540
DPPPPPSEAE DSDRDVSSDS SMR 563 
Gene Ontology
 GO:0005882; C:intermediate filament; IEA:UniProtKB-KW. 
Interpro
 IPR026665; Iffo1/2. 
Pfam
  
SMART
  
PROSITE
  
PRINTS