UniProt Accession

 E5RFH6_HUMAN; E5RFH6 

Genbank Protein ID

 AF311103 

Genbank Nucleotide ID

  

Protein Name

 Lipid-phosphate phosphatase 

Protein Synonyms/Alias

  

Gene Name

 EPHX2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
43	LLNDAFQKGGPEGAT	ubiquitination	[1, 2, 3]
223	QNLSRTFKSLFRASD	ubiquitination	[2]
238	ESVLSMHKVCEAGGL	ubiquitination	[2]
272	QFYVQQFKKSGFRGP	ubiquitination	[2]
273	FYVQQFKKSGFRGPL	ubiquitination	[2]
291	RNMERNWKWACKSLG	ubiquitination	[2]
295	RNWKWACKSLGRKIL	ubiquitination	[2]
300	ACKSLGRKILIPALM	ubiquitination	[2]
332	EDWIPHLKRGHIEDC	ubiquitination	[2]
347	GHWTQMDKPTEVNQI	ubiquitination	[2]
371	RNPPVVSKM******	ubiquitination	[2]

Reference

 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 372 AA 

Protein Sequence

Gene Ontology

 GO:0005925; C:focal adhesion; IDA:HPA.
 GO:0005794; C:Golgi apparatus; IDA:HPA.
 GO:0005730; C:nucleolus; IDA:HPA.
 GO:0003824; F:catalytic activity; IEA:InterPro.
 GO:0008152; P:metabolic process; IEA:GOC. 

Interpro

 IPR000073; AB_hydrolase_1.
 IPR000639; Epox_hydrolase-like.
 IPR023214; HAD-like_dom.
 IPR023198; PGP_dom2. 

Pfam

 PF00561; Abhydrolase_1 

SMART

  

PROSITE

  

PRINTS

 PR00111; ABHYDROLASE.
 PR00412; EPOXHYDRLASE.