CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025460
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc fingers and homeoboxes 3 
Protein Synonyms/Alias
 Zinc fingers and homeoboxes 3, isoform CRA_a 
Gene Name
 Zhx3 
Gene Synonyms/Alias
 mCG_52843 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
721ERKVSPIKINLKNLRubiquitination[1]
725SPIKINLKNLRVTEAubiquitination[1]
761LVEQPPSKVSYKKTAubiquitination[1]
815GDSRYALKNGQLKWYubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 DNA-binding; Homeobox; Nucleus. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 951 AA 
Protein Sequence
MASKRKSTTP CMIPVKTVVL PGASTEPQPV ESLPEGPQQD LPSEAPDASS EAAPNPSSTD 60
GSALANGHRS TLDGYVYCCK ECEFRSQDVT HFIGHMNSEH TDFNKDPTFV CTGCSFLAKN 120
PEGLSLHNAK CHSGEASFLW NVTKPDNHVV VEQSVPDSAS SSVLAGESTT EGTEIIITKT 180
PIMKIMKGKA EAKKIHMLKE NAPNQPGSEA LPKPLAGERE VKEGDHTFIN GAAPGSQASA 240
KSTKPPPAAN GPLIGTVPVL PAGIAQFLSL QQQPPVHAQH HTHQPLPTSK TLPKVMIPLS 300
SIPTYNAAMD SNSFLKNSFH KFPYPTKAEL CYLTVVTKYP EEQLKIWFTA QRLKQGISWS 360
PEEIEDARKK MFNTVIQSVP QPTITVLNTP LVASAGNVQH LIQATLPGHA VGQPEGTAGG 420
LLVTQPLMAN GLQASSSSLP LTTASVPKPT VAPINTVCSN SASAVKVVNA AQSLLTACPS 480
ITSQAFLDAN IYKNKKSHEQ LSALKGSFCR NQFPGQSEVE HLTKVTGLST REVRKWFSDR 540
RYHCRNLKGS RAMMPGEHGS VLIDSVPEVP FPLASKVPEV TCIPTATSLV SHPATKRQSW 600
HQTPDFTPTK YKERAPEQLR VLENSFAQNP LPPEEELDRL RSETKMTRRE IDGWFSERRK 660
KVNTEETKKA DGHMPKEEEE GAEQEGRDEE LANELRVPGE NGSPEMFLSH ALAERKVSPI 720
KINLKNLRVT EASGKSEFPG MGVCEPEEDG LNKLVEQPPS KVSYKKTAQQ RHLLRQLFVQ 780
TQWPSNQDYD SIMAQTGLPR PEVVRWFGDS RYALKNGQLK WYEDYKRGNF PPGLLVIAPG 840
NRELLQDYYM THKMLCEEDL QTLCDKTQMS AQQVKQWFAE KMGEETRAVA DISSEDQGPR 900
NGEPVAVHKV LGDAYSELSE NSESWEPSAP EASSEPFDTS SPQSGRQLEA D 951 
Gene Ontology
 GO:0005938; C:cell cortex; ISO:MGI.
 GO:0005730; C:nucleolus; IEA:Compara.
 GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0003714; F:transcription corepressor activity; IEA:Compara.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0045669; P:positive regulation of osteoblast differentiation; IEA:Compara. 
Interpro
 IPR001356; Homeodomain.
 IPR009057; Homeodomain-like.
 IPR015880; Znf_C2H2-like. 
Pfam
 PF00046; Homeobox 
SMART
 SM00389; HOX
 SM00355; ZnF_C2H2 
PROSITE
 PS50071; HOMEOBOX_2 
PRINTS