CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010183
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Glutathione import ATP-binding protein GsiA 
Protein Synonyms/Alias
  
Gene Name
 gsiA 
Gene Synonyms/Alias
 yliA; b0829; JW5897 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
437VHGLLPGKDAAARVAacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 Part of the ABC transporter complex GsiABCD involved in glutathione import. Responsible for energy coupling to the transport system. 
Sequence Annotation
 DOMAIN 15 269 ABC transporter 1.
 DOMAIN 314 564 ABC transporter 2.
 NP_BIND 49 56 ATP (Potential).
 NP_BIND 357 364 ATP (Potential).  
Keyword
 ATP-binding; Cell inner membrane; Cell membrane; Complete proteome; Hydrolase; Membrane; Nucleotide-binding; Reference proteome; Repeat; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 623 AA 
Protein Sequence
MPHSDELDAG NVLAVENLNI AFMQDQQKIA AVRNLSFSLQ RGETLAIVGE SGSGKSVTAL 60
ALMRLLEQAG GLVQCDKMLL QRRSREVIEL SEQNAAQMRH VRGADMAMIF QEPMTSLNPV 120
FTVGEQIAES IRLHQNASRE EAMVEAKRML DQVRIPEAQT ILSRYPHQLS GGMRQRVMIA 180
MALSCRPAVL IADEPTTALD VTIQAQILQL IKVLQKEMSM GVIFITHDMG VVAEIADRVL 240
VMYQGEAVET GTVEQIFHAP QHPYTRALLA AVPQLGAMKG LDYPRRFPLI SLEHPAKQAP 300
PIEQKTVVDG EPVLRVRNLV TRFPLRSGLL NRVTREVHAV EKVSFDLWPG ETLSLVGESG 360
SGKSTTGRAL LRLVESQGGE IIFNGQRIDT LSPGKLQALR RDIQFIFQDP YASLDPRQTI 420
GDSIIEPLRV HGLLPGKDAA ARVAWLLERV GLLPEHAWRY PHEFSGGQRQ RICIARALAL 480
NPKVIIADEA VSALDVSIRG QIINLLLDLQ RDFGIAYLFI SHDMAVVERI SHRVAVMYLG 540
QIVEIGPRRA VFENPQHPYT RKLLAAVPVA EPSRQRPQRV LLSDDLPSNI HLRGEEVAAV 600
SLQCVGPGHY VAQPQSEYAF MRR 623 
Gene Ontology
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0043492; F:ATPase activity, coupled to movement of substances; IMP:EcoCyc.
 GO:0034775; P:glutathione transmembrane transport; IMP:EcoCyc. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR003439; ABC_transporter-like.
 IPR017871; ABC_transporter_CS.
 IPR013563; Oligopep_ABC_C.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00005; ABC_tran
 PF08352; oligo_HPY 
SMART
 SM00382; AAA 
PROSITE
 PS00211; ABC_TRANSPORTER_1
 PS50893; ABC_TRANSPORTER_2 
PRINTS