UniProt Accession

 NDUBA_MOUSE; Q9DCS9; Q3UAE3 

Genbank Protein ID

 AK002517; AK151404; BC031664; BC043013 

Genbank Nucleotide ID

 BAB22156.1; BAE30371.1; AAH31664.1; AAH43013.1 

Protein Name

 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 

Protein Synonyms/Alias

 Complex I-PDSW; CI-PDSW; NADH-ubiquinone oxidoreductase PDSW subunit 

Gene Name

 Ndufb10 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
7	*MPDSWDKDVYPEPP	acetylation	[1]
134	KELEQFTKVTKAYQD	acetylation	[1, 2, 3]

Reference

 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123]
 [2] The fasted/fed mouse metabolic acetylome: N6-acetylation differences suggest acetylation coordinates organ-specific fuel switching.
 Yang L, Vaitheesvaran B, Hartil K, Robinson AJ, Hoopmann MR, Eng JK, Kurland IJ, Bruce JE.
 J Proteome Res. 2011 Sep 2;10(9):4134-49. [PMID: 21728379]
 [3] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654] 

Functional Description

 Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). 

Sequence Annotation

  

Keyword

 Complete proteome; Direct protein sequencing; Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Respiratory chain; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 176 AA 

Protein Sequence

Gene Ontology

 GO:0005743; C:mitochondrial inner membrane; IDA:MGI.
 GO:0005747; C:mitochondrial respiratory chain complex I; IEA:Compara.
 GO:0022900; P:electron transport chain; IEA:UniProtKB-KW. 

Interpro

 IPR019377; NADH_UbQ_OxRdtase_su10. 

Pfam

 PF10249; NDUFB10 

SMART

  

PROSITE

  

PRINTS