CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018954
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative fatty acyl-CoA reductase CG8306 
Protein Synonyms/Alias
  
Gene Name
 CG8306 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
456GVRQYLSKEPIKNLEacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
 Catalyzes the reduction of saturated fatty acyl-CoA to fatty alcohols (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Lipid biosynthesis; Lipid metabolism; Membrane; NADP; Oxidoreductase; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 516 AA 
Protein Sequence
MASSPITDFY AGRNVFITGA TGFVGVTIVE KLLRDVPNVG TLYLLMRAKK GKSVQERLEE 60
LKKNSVFDKF KELQLQSRLS KIVPIEGDVG LEHLGISPKD RQTLIDNVNV VFHSAATLDF 120
FQSLKETTNI NLRGTRRVVE LCQQIKNLDA LVHVSSAYVN AYLTKVEEKL YPAPEDPEKI 180
IQLSETLNDD ALKELEPKLL KDHPNTYTFT KHLAEHEVAN VASKFPCGIV RPSMITAAWK 240
EPIPGWTISK NGPQGFFMGA SKGVLRRLPL DPSIIMDYIP IDVVVNGIIT TGYYVNSLQA 300
KNGGRPADLQ IFHLTSSTYK PFRFELMTDK INSYLHDYPL NSAVWYPNLR LVKSLWVFRL 360
SAILFHFIPA IILDLVTKIG GGRPILVRLH KNVWNSLNTL EKFIFTEWHF DSKRLLALSK 420
TLNIVDKKKF FIDIGELAWD EYFSNTILGV RQYLSKEPIK NLEKARRKDK ILLGLHVALQ 480
LSFWYGVFKL IVCLTGISTA KAALVLPVLY YLFGLL 516 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005777; C:peroxisome; ISS:UniProtKB.
 GO:0080019; F:fatty-acyl-CoA reductase (alcohol-forming) activity; IEA:InterPro.
 GO:0050062; F:long-chain-fatty-acyl-CoA reductase activity; ISS:UniProtKB.
 GO:0010025; P:wax biosynthetic process; ISS:UniProtKB. 
Interpro
 IPR026055; FAR.
 IPR013120; Male_sterile_NAD-bd.
 IPR016040; NAD(P)-bd_dom. 
Pfam
 PF07993; NAD_binding_4
 PF03015; Sterile 
SMART
  
PROSITE
  
PRINTS