CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032288
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 CLASP1 protein 
Protein Synonyms/Alias
 CLIP-associating protein 1; Uncharacterized protein 
Gene Name
 CLASP1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
228TKFDEVQKSGNMIQSubiquitination[1]
493VLAETIKKGIHDADSubiquitination[2]
851SSNWSERKEGLLGLQubiquitination[2, 3]
978KVKVAILKYIESLARubiquitination[3]
1130GVTEAIEKFSFRSQEubiquitination[3]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1477 AA 
Protein Sequence
MEPRMESCLA QVLQKDVGKR LQVGQELIDY FSDKQKSADL EHDQTMLDKL VDGLATSWVN 60
SSNYKVVLLG MDILSALVTR LQDRFKAQIG TVLPSLIDRL GDAKDSVREQ DQTLLLKIMD 120
QAANPQYVWD RMLGGFKHKN FRTREGICLC LIATLNASGA QTLTLSKIVP HICNLLGDPN 180
SQVRDAAINS LVEIYRHVGE RVRADLSKKG LPQSRLNVIF TKFDEVQKSG NMIQSANDKN 240
FDDEDSVDGN RPSSASSTSS KAPPSSRRNV GMGTTRRLGS STLGSKSSAA KEGAGAVDEE 300
DFIKAFDDVP VVQIYSSRDL EESINKIREI LSDDKHDWEQ RVNALKKIRS LLLAGAAEYD 360
NFFQHLRLLD GAFKLSAKDL RSQVVREACI TLGHLSSVLG NKFDHGAEAI MPTIFNLIPN 420
SAKIMATSGV VAVRLIIRHT HIPRLIPVIT SNCTSKSVAV RRRCFEFLDL LLQEWQTHSL 480
ERHISVLAET IKKGIHDADS EARIEARKCY WGFHSHFSRE AEHLYHTLES SYQKALQSHL 540
KNSDSIVSLP QSDRSSSSSQ ESLNRPLSAK RSPTGSTTSR ASTVSTKSVS TTGSLQRSRS 600
DIDVNAAASA KSKVSSSSGT TPFSSAAALP PGSYASLESR HMREDMEYIG LDSGRIRTRR 660
QSSGSATNVA STPDNRGRSR AKVVSQSQPG SRSSSPGKLL GSGYGGLTGG SSRGPPVTPS 720
SEKRSKIPRS QGCSRETSPN RIGLDRFGLG QPGRIPGSVN AMRVLSTSTD LEAAVADALL 780
LGDSRSKKPV RRRYEPYGMY SDDDANSDAS SVCSERSYGS RNGGIPHYLR QTEDVAEVLN 840
HCASSNWSER KEGLLGLQNL LKSQRTLSRV ELKRLCEIFT RMFADPHSKR VFSMFLETLV 900
DFIIIHKDDL QDWLFVLLTQ LLKKMGADLL GSVQAKVQKA LDVTRDSFPF DQQFNILMRF 960
IVDQTQTPNL KVKVAILKYI ESLARQMDPT DFVNSSETRL AVSRIITWTT EPKSSDVRKA 1020
AQIVLISLFE LNTPEFTMLL GALPKTFQDG ATKLLHNHLK NSSNTSVGSP SNTIGRTPSR 1080
HTSSRTSPLT SPTNCSHGGL SPSMLDYDTE NLNSEEIYSS LRGVTEAIEK FSFRSQEDLN 1140
EPIKRDGKKE CDIVSRDGGA ASPATEGRGG SEVEGGRTAL DNKTSLLNTQ PPRAFPGPRA 1200
RDYNPYPYSD AINTYDKTAL KEAVFDDDME QLRDVPIDHS DLVADLLKEL SNHNERVEER 1260
KGALLELLKI TREDSLGVWE EHFKTILLLL LETLGDKDHS IRALALRVLR EILRNQPARF 1320
KNYAELTIMK TLEAHKDSHK EVVRAAEEAA STLASSIHPE QCIKVLCPII QTADYPINLA 1380
AIKMQTKVVE RIAKESLLQL LVDIIPGLLQ GYDNTESSVR KASVFCLVAI YSVIGEDLKP 1440
HLAQLTGSKM KLLNLYIKRA QTTNSNSSSS SDVSTHS 1477 
Gene Ontology
  
Interpro
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR024395; CLASP_N_dom.
 IPR021133; HEAT_type_2. 
Pfam
 PF12348; CLASP_N 
SMART
  
PROSITE
 PS50077; HEAT_REPEAT 
PRINTS