CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039351
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 NEDD8-activating enzyme E1 regulatory subunit 
Protein Synonyms/Alias
  
Gene Name
 Nae1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
6**MAQQGKILKEQKYacetylation[1]
338DMIADSSKYIKLQNVubiquitination[2]
378APESISEKELKLLCSacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 534 AA 
Protein Sequence
MAQQGKILKE QKYDRQLRLW GDHGQEALES AHVCLINATA TGTEILKNLV LPGIGSFTII 60
DGNQVSGEDV VNHFFLQKCS IGKNRAQAAM EFLQELNSDV SGSFVEESPE NLLDNDPSFF 120
CRFTIVVATQ LLESTLLRLA DVLWNSQIPL LICRTYGLVG YMRIIIKEHP VIESHPDNAL 180
EDLRLDKPFP ELREHFQSYD LDHMEKKDHS HTPWIVIIAK YLAQWYSETN GRIPKSYKEK 240
EDFRELIRQG ILKNENGAPE DEENFEEAIK NVNTALNTTQ IPSSIEDIFN DDRCINITKQ 300
TPSFWILARA LKEFVAKEGQ GNLPVRGTIP DMIADSSKYI KLQNVYREKA KKDAAAVGNH 360
VAKLLQSVGQ APESISEKEL KLLCSNSAFL RVVRCRSLAE EYGLHTVNKD EIISSMDNPD 420
NEIVLYLMLR AVDRFHKQHG RYPGVSNYQV EEDIGKLKSC LTDFLQEYGL SVMVKDDYVH 480
EFCRYRAAEP HTIAAFLGGA ATQEVIKIIT KQFVIFNNTY IYSGMSQTSA TFQL 534 
Gene Ontology
 GO:0003824; F:catalytic activity; IEA:InterPro.
 GO:0008152; P:metabolic process; IEA:GOC. 
Interpro
 IPR009036; Molybdenum_cofac_synth_MoeB.
 IPR016040; NAD(P)-bd_dom.
 IPR000594; ThiF_NAD_FAD-bd. 
Pfam
 PF00899; ThiF 
SMART
  
PROSITE
  
PRINTS