CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021514
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 395 
Protein Synonyms/Alias
 HD-regulating factor 2; HDRF-2; Huntington disease gene regulatory region-binding protein 2; HD gene regulatory region-binding protein 2; HDBP-2; Papillomavirus regulatory factor 1; PRF-1; Papillomavirus-binding factor 
Gene Name
 ZNF395 
Gene Synonyms/Alias
 HDBP2; PBF 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
289CLWPNCGKVLRSIVGubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
 Plays a role in papillomavirus genes transcription. 
Sequence Annotation
 ZN_FING 280 305 C2H2-type.
 MOTIF 165 174 Nuclear export signal (Potential).
 MOD_RES 248 248 Phosphoserine.  
Keyword
 Complete proteome; Cytoplasm; DNA-binding; Metal-binding; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 513 AA 
Protein Sequence
MASVLSRRLG KRSLLGARVL GPSASEGPSA APPSEPLLEG AAPQPFTTSD DTPCQEQPKE 60
VLKAPSTSGL QQVAFQPGQK VYVWYGGQEC TGLVEQHSWM EGQVTVWLLE QKLQVCCRVE 120
EVWLAELQGP CPQAPPLEPG AQALAYRPVS RNIDVPKRKS DAVEMDEMMA AMVLTSLSCS 180
PVVQSPPGTE ANFSASRAAC DPWKESGDIS DSGSSTTSGH WSGSSGVSTP SPPHPQASPK 240
YLGDAFGSPQ TDHGFETDPD PFLLDEPAPR KRKNSVKVMY KCLWPNCGKV LRSIVGIKRH 300
VKALHLGDTV DSDQFKREED FYYTEVQLKE ESAAAAAAAA AGTPVPGTPT SEPAPTPSMT 360
GLPLSALPPP LHKAQSSGPE HPGPESSLPS GALSKSAPGS FWHIQADHAY QALPSFQIPV 420
SPHIYTSVSW AAAPSAACSL SPVRSRSLSF SEPQQPAPAM KSHLIVTSPP RAQSGARKAR 480
GEAKKCRKVY GIEHRDQWCT ACRWKKACQR FLD 513 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:UniProtKB.
 GO:0005634; C:nucleus; IDA:UniProtKB.
 GO:0003677; F:DNA binding; IDA:UniProtKB.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IC:UniProtKB.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like. 
Pfam
  
SMART
 SM00355; ZnF_C2H2 
PROSITE
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS