| Tag | Content |
|---|
| CPLM ID | CPLM-007347 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Kinetochore protein NDC80 |
Protein Synonyms/Alias | Protein TID3 |
Gene Name | TID3 |
Gene Synonyms/Alias | HEC1; NDC80; YIL144W |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 231 | WMVRTNIKLDMCLNK | sumoylation | [1] |
|
Reference | [1] Sumoylation of the budding yeast kinetochore protein Ndc10 is required for Ndc10 spindle localization and regulation of anaphase spindle elongation. Montpetit B, Hazbun TR, Fields S, Hieter P. J Cell Biol. 2006 Aug 28;174(5):653-63. [ PMID: 16923829] |
Functional Description | Acts as a component of the essential kinetochore- associated NDC80 complex, which is involved in chromosome segregation and spindle checkpoint activity. |
Sequence Annotation | MOD_RES 38 38 Phosphothreonine.
MOD_RES 248 248 Phosphothreonine. |
Keyword | Cell cycle; Cell division; Centromere; Chromosome; Coiled coil; Complete proteome; Kinetochore; Mitosis; Nucleus; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 691 AA |
Protein Sequence | MQSSTSTDQH VLHHMDPHRF TSQIPTATSS QLRRRNSTNQ GLTDMINKSI ARNTISGTGI 60
PTGGINKNKR TRSTVAGGTN GTALALNDKS NSRNSVSRLS INQLGSLQQH LSNRDPRPLR 120
DKNFQSAIQE EIYDYLKKNK FDIETNHPIS IKFLKQPTQK GFIIIFKWLY LRLDPGYGFT 180
KSIENEIYQI LKNLRYPFLE SINKSQISAV GGSNWHKFLG MLHWMVRTNI KLDMCLNKVD 240
RSLINQNTQE ITILSQPLKT LDEQDQRQER YELMVEKLLI DYFTESYKSF LKLEDNYEPS 300
MQELKLGFEK FVHIINTDIA NLQTQNDNLY EKYQEVMKIS QKIKTTREKW KALKSDSNKY 360
ENYVNAMKQK SQEWPGKLEK MKSECELKEE EIKALQSNIS ELHKILRKKG ISTEQFELQN 420
QEREKLTREL DKINIQSDKL TSSIKSRKLE AEGIFKSLLD TLRQYDSSIQ NLTRSRSQLG 480
HNVNDSSLKI NISENLLDRD FHEGISYEQL FPKGSGINES IKKSILKLND EIQERIKTIE 540
KDNITLEKDI KNLKHDINEK TQINEKLELE LSEANSKFEL SKQENERLLV AQRIEIEKME 600
KKINDSNLLM KTKISDAEEL VTSTELKLEE LKVDLNRKRY KLHQQVIHVI DITSKFKINI 660
QSSLENSENE LGNVIEELRN LEFETEHNVT N 691 |
Gene Ontology | GO:0000778; C:condensed nuclear chromosome kinetochore; IDA:SGD. GO:0031262; C:Ndc80 complex; IDA:SGD. GO:0005200; F:structural constituent of cytoskeleton; IPI:SGD. GO:0051301; P:cell division; IEA:UniProtKB-KW. GO:0007059; P:chromosome segregation; IMP:SGD. GO:0007020; P:microtubule nucleation; IPI:SGD. GO:0007067; P:mitosis; IEA:UniProtKB-KW. GO:0034501; P:protein localization to kinetochore; IMP:SGD. |
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PRINTS | |