CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044341
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Septin-1 
Protein Synonyms/Alias
  
Gene Name
 SEPT1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
354RMQEMLEKMQAQMQQubiquitination[1, 2]
Reference
 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; GTP-binding; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 372 AA 
Protein Sequence
MAGGVMDKEY VGFAALPNQL HRKSVKKGFD FTLMVAGESG LGKSTLINSL FLTNLYEDRQ 60
VPEASARLTQ TLAIERRGVE IEEGGVKVKL TLVDTPGFGD SVDCSDCWLP VVKFIEEQFE 120
QYLRDESGLN RKNIQDSRVH CCLYFISPFG RGLRPLDVAF LRAVHEKVNI IPVIGKADAL 180
MPQETQALKQ KIRDQLKEEE IHIYQFPECD SDEDEDFKRQ DAEMKESIPF AVVGSCEVVR 240
DGGNRPVRGR RYSWGTVEVE NPHHCDFLNL RRMLVQTHLQ DLKEVTHDLL YEGYRARCLQ 300
SLARPGARDR ASRSKLSRQS ATEIPLPMLP LADTEKLIRE KDEELRRMQE MLEKMQAQMQ 360
QSQAQGEQSD AL 372 
Gene Ontology
 GO:0031105; C:septin complex; IEA:InterPro.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0007049; P:cell cycle; IEA:InterPro. 
Interpro
 IPR000038; Cell_div_GTP-bd.
 IPR027417; P-loop_NTPase.
 IPR016491; Septin. 
Pfam
 PF00735; Septin 
SMART
  
PROSITE
  
PRINTS