CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010383
UniProt Accession
Genbank Protein ID
 U00089 
Genbank Nucleotide ID
Protein Name
 Translation initiation factor IF-3 
Protein Synonyms/Alias
  
Gene Name
 infC 
Gene Synonyms/Alias
 MPN_115; MP039 
Created Date
 July 27, 2013 
Organism
 Mycoplasma pneumoniae (strain ATCC 29342 / M129) 
NCBI Taxa ID
 272634 
Lysine Modification
Position
Peptide
Type
References
34SRREREQKPLINDKIacetylation[1]
Reference
 [1] Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.
 van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC.
 Mol Syst Biol. 2012 Feb 28;8:571. [PMID: 22373819
Functional Description
 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Cytoplasm; Initiation factor; Protein biosynthesis; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 201 AA 
Protein Sequence
MPLILDQGCF VSESRFHRLA QNIKQGSRRE REQKPLINDK IGFNEFILID ENGSNLGTVR 60
RTDALKMAEE KQLDLVLIGS NPAKPIVKLL DFGRYTYDLK RKKRQSKKNQ TIIQIKEVVV 120
KPTIAKHDLE FKAKQTTGWA EKGYHVKFVV RAFGRVSTRI ELIEKVFNDF YLLVEPAVEV 180
QKPLTASSKT MYSALLVPRK K 201 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0003743; F:translation initiation factor activity; IEA:HAMAP. 
Interpro
 IPR019813; Translation_initiation_fac3_CS.
 IPR001288; Translation_initiation_fac_3.
 IPR019815; Translation_initiation_fac_3_C.
 IPR019814; Translation_initiation_fac_3_N. 
Pfam
 PF00707; IF3_C
 PF05198; IF3_N 
SMART
  
PROSITE
 PS00938; IF3 
PRINTS