| Tag | Content |
|---|
| CPLM ID | CPLM-006861 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | AP-3 complex subunit mu |
Protein Synonyms/Alias | AP-3 adapter complex mu3A subunit; Adapter-related protein complex 3 mu subunit; Mu-adaptin 3A; Mu3-adaptin |
Gene Name | APM3 |
Gene Synonyms/Alias | YKS6; YBR288C; YBR2035 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 113 | KDKLSIKKIVNNYDR | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Part of the AP-3 complex, an adapter-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to the vacuole. Required for the transport via the ALP pathway, which directs the transport of the cargo proteins PHO8 and VAM3 to the vacuole. |
Sequence Annotation | DOMAIN 211 482 MHD. |
Keyword | Complete proteome; Cytoplasmic vesicle; Golgi apparatus; Membrane; Protein transport; Reference proteome; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 483 AA |
Protein Sequence | MYLSFYITDT KNKLIFQYLL GATAPSFKHL WTRVQSTCPQ LLEDSSSDDY LDHSMVGRDL 60
EVYKYFSVIN KLNYWCLAST SKSKGPLDCF TFLETIDRIL LEYFDKDKLS IKKIVNNYDR 120
ISLIFNCCVE AGEPNVSDML YVNKIKEAVP ERSDLSKFIS STAHNLQQAV QLPQQRQQQL 180
QQNQISRGSN SLIENEEIVP WRTSRASKHE NNELYVDLLE TFHVVFEKKK SHLRLLTGSI 240
HGIVDVRSYL NDNPLVAVKL NTMGNDIGIP SLHDCVEIND GVFSPSNITF IPPDGKFRLL 300
EYSVDLSSQV KQSGVRMNSI GLMSLHFQNG LGKDSDEFEL SLNIENFKKV SQVDDLKIDL 360
QFNVENADPN EIAYKIKILR NTHGRFENSI IMGQGQWIFD KSTATGTVPV LRGCIEYENT 420
GPNFTKKVDL QTVSLEYSYI GQSASGIYVE AIDIVSGLTI GKNTKLYKGA KYKTQTGNFQ 480
VRL 483 |
Gene Ontology | GO:0030123; C:AP-3 adaptor complex; IDA:SGD. GO:0030131; C:clathrin adaptor complex; IEA:InterPro. GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell. GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell. GO:0006896; P:Golgi to vacuole transport; IMP:SGD. GO:0006623; P:protein targeting to vacuole; IMP:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |