CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018291
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Sorting nexin-33 
Protein Synonyms/Alias
 SH3 and PX domain-containing protein 3 
Gene Name
 SNX33 
Gene Synonyms/Alias
 SH3PX3; SH3PXD3C; SNX30 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
350MGKRRAEKDEMVGASacetylation[1]
382EDRVDTFKAFSKKMDacetylation[1]
386DTFKAFSKKMDDSVLacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
  
Sequence Annotation
 DOMAIN 1 61 SH3.
 DOMAIN 230 340 PX.
 DOMAIN 371 574 BAR.
 MOD_RES 77 77 Phosphoserine.  
Keyword
 3D-structure; Complete proteome; Phosphoprotein; Reference proteome; SH3 domain. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 574 AA 
Protein Sequence
MALKGRALYD FHSENKEEIS IQQDEDLVIF SETSLDGWLQ GQNSRGETGL FPASYVEIVR 60
SGISTNHADY SSSPAGSPGA QVSLYNSPSV ASPARSGGGS GFLSNQGSFE EDDDDDWDDW 120
DDGCTVVEEP RAGGLGTNGH PPLNLSYPGA YPSQHMAFRP KPPLERQDSL ASAKRGSVVG 180
RNLNRFSCFV RSGVEAFILG DVPMMAKIAE TYSIEMGPRG PQWKANPHPF ACSVEDPTKQ 240
TKFKGIKSYI SYKLTPTHAA SPVYRRYKHF DWLYNRLLHK FTVISVPHLP EKQATGRFEE 300
DFIEKRKRRL ILWMDHMTSH PVLSQYEGFQ HFLSCLDDKQ WKMGKRRAEK DEMVGASFLL 360
TFQIPTEHQD LQDVEDRVDT FKAFSKKMDD SVLQLSTVAS ELVRKHVGGF RKEFQKLGSA 420
FQAISHSFQM DPPFCSEALN SAISHTGRTY EAIGEMFAEQ PKNDLFQMLD TLSLYQGLLS 480
NFPDIIHLQK GAFAKVKESQ RMSDEGRMVQ DEADGIRRRC RVVGFALQAE MNHFHQRREL 540
DFKHMMQNYL RQQILFYQRV GQQLEKTLRM YDNL 574 
Gene Ontology
 GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
 GO:0007154; P:cell communication; IEA:InterPro. 
Interpro
 IPR001683; Phox.
 IPR001452; SH3_domain.
 IPR014536; Snx9.
 IPR019497; Sorting_nexin_WASP-bd-dom. 
Pfam
 PF10456; BAR_3_WASP_bdg
 PF00787; PX
 PF00018; SH3_1 
SMART
 SM00312; PX
 SM00326; SH3 
PROSITE
 PS51021; BAR
 PS50195; PX
 PS50002; SH3 
PRINTS