CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002876
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transcriptional repressor NrdR 
Protein Synonyms/Alias
  
Gene Name
 nrdR 
Gene Synonyms/Alias
 STM0415 
Created Date
 July 27, 2013 
Organism
 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 
NCBI Taxa ID
 99287 
Lysine Modification
Position
Peptide
Type
References
117NLVMEQLKKLDKVAYacetylation[1]
118LVMEQLKKLDKVAYIacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786
Functional Description
 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity). 
Sequence Annotation
 DOMAIN 49 139 ATP-cone.
 ZN_FING 3 34 By similarity.  
Keyword
 ATP-binding; Complete proteome; DNA-binding; Metal-binding; Nucleotide-binding; Reference proteome; Repressor; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 149 AA 
Protein Sequence
MHCPFCFAVD TKVIDSRLVG EGSSVRRRRQ CLVCNERFTT FEVAELVMPR VIKSNDVREP 60
FNEDKLRSGM LRALEKRPVS ADDVEMALNH IKSQLRATGE REVPSKMIGN LVMEQLKKLD 120
KVAYIRFASV YRSFEDIKDF GEEIARLQD 149 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:HAMAP.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:HAMAP.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; IEA:HAMAP.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR005144; ATP-cone.
 IPR003796; RNR_NrdR-like. 
Pfam
 PF03477; ATP-cone 
SMART
  
PROSITE
 PS51161; ATP_CONE 
PRINTS