CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030262
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transporter 
Protein Synonyms/Alias
  
Gene Name
 Slc6a5 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
743GRFIERLKLVCSPQPubiquitination[1]
779GTSSLGLKLPVKDLEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Membrane; Reference proteome; Symport; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 791 AA 
Protein Sequence
MNKQPANILE AAVPGHRDSP RAPRTSPEQD LPAEAPTATV QPPRVPRSAS TGAQTFQSAD 60
ARACEAQQSG VGFCNLSSPR AQATSAALRD LSEGHSAQAN PPSGPAGAGN ALHCKIPALR 120
GPEEDANVSV GKGTLEHNNT PAVGWVNMSQ STVVLGTDGI ASVLPGSVAT TTIPEDEQGD 180
ENKARGNWSS KLDFILSMVG YAVGLGNVWR FPYLAFQNGG GAFLIPYLMM LALAGLPIFF 240
LEVSLGQFAS QGPVSVWKAI PALQGCGIAM LIISVLIAIY YNVIICYTLF YLFASFVSVL 300
PWGSCNNPWN TPECKDKTKL LLDSCVIGDH PKIQIKNSTF CMTAYPNLTM VNFTSQTNKT 360
FVSGSEEYFK YFVLKISAGI EYPGEIRWPL AFCLFLAWVI VYASLAKGIK SSGKVVYFTA 420
TFPYVVLVIL LIRGVTLPGA GAGIWYFITP KWEKLTDATV WKDAATQIFF SLSAAWGGLI 480
TLSSYNKFHN NCYRDTLIVT CTNSATSIFA GFVIFSVIGF MANERKVNIE NVADQGPGIA 540
FVVYPEALTR LPLSPFWAII FFLMLLTLGL DTMFATIETI VTSISDEFPK YLRTHKPVFT 600
LGCCICFFIM GFPMITQGGI YMFQLVDTYA ASYALVIIAI FELVGISYVY GLQRFCEDIE 660
MMIGFKPNIF WKVCWAFVTP TILTFILCFS FYQWEPMTYG SYRYPNWSMV LGWLMLACSV 720
IWIPIMFVIK MYLAPGRFIE RLKLVCSPQP DWGPFLAQHR GERYKNMIDP LGTSSLGLKL 780
PVKDLELGTQ C 791 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro. 
Interpro
 IPR000175; Na/ntran_symport. 
Pfam
 PF00209; SNF 
SMART
  
PROSITE
 PS00610; NA_NEUROTRAN_SYMP_1
 PS00754; NA_NEUROTRAN_SYMP_2
 PS50267; NA_NEUROTRAN_SYMP_3 
PRINTS
 PR00176; NANEUSMPORT.