CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042989
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Tetratricopeptide repeat protein 8 
Protein Synonyms/Alias
  
Gene Name
 TTC8 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
34DQAAWILKARALTEMubiquitination[1]
173STEHSQYKDWWWKVQubiquitination[1]
183WWKVQIGKCYYRLGMubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat; TPR repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 437 AA 
Protein Sequence
XWSYFRRRKF QLCADLCTQM LEKSPYDQAA WILKARALTE MVYIDEIDVD QEGIAEMMLD 60
ENAIAQVPRP GTSLKLPGTN QTGGPSQAVR PITQAGRPIT GFLRPSTQSG RPGTMEQAIR 120
TPRTAYTARP ITSSSGRFVR LGTALFEYIF HHENDVKTAL DLAALSTEHS QYKDWWWKVQ 180
IGKCYYRLGM YREAEKQFKS ALKQQEMVDT FLYLAKVYVS LDQPVTALNL FKQGLDKFPG 240
EVTLLCGIAR IYEEMNNMSS AAEYYKEVLK QDNTHVEAIA CIGSNHFYSD QPEIALRFYR 300
RLLQMGIYNG QLFNNLGLCC FYAQQYDMTL TSFERALSLA ENEEEAADVW YNLGHVAVGI 360
GDTNLAHQCF RLALVNNNNH AEAYNNLAVL EMRKGHVEQI GDLQRSYVAA QKSEAAFPDH 420
VDTQHLIKQL RQHFAML 437 
Gene Ontology
  
Interpro
 IPR001440; TPR-1.
 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical.
 IPR019734; TPR_repeat. 
Pfam
 PF00515; TPR_1 
SMART
 SM00028; TPR 
PROSITE
 PS50005; TPR
 PS50293; TPR_REGION 
PRINTS