| Tag | Content |
|---|
| CPLM ID | CPLM-017768 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Microtubule-associated protein RP/EB family member 2 |
Protein Synonyms/Alias | APC-binding protein EB2; End-binding protein 2; EB2 |
Gene Name | Mapre2 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 125 | KLLQASFKRMNVDKV | ubiquitination | [1] | | 137 | DKVIPVEKLVKGRFQ | ubiquitination | [1] | | 164 | YDANYDGKEYDPVEA | ubiquitination | [1] | | 270 | ERDFYFGKLREIELL | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration (By similarity). |
Sequence Annotation | DOMAIN 56 158 CH.
DOMAIN 235 305 EB1 C-terminal.
REGION 186 326 DCTN1-binding (By similarity).
REGION 258 301 APC-binding (By similarity).
MOD_RES 166 166 Phosphotyrosine.
MOD_RES 218 218 Phosphoserine (By similarity). |
Keyword | Alternative splicing; Cell cycle; Cell division; Complete proteome; Cytoplasm; Cytoskeleton; Microtubule; Mitosis; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 326 AA |
Protein Sequence | MPGPTQTLSP NGENNNDIIQ DNGTIIPFRK HTVRGERSYS WGMAVNVYST SITQETMSRH 60
DIIAWVNDIV SLNYTKVEQL CSGAAYCQFM DMLFPGCISL KKVKFQAKLE HEYIHNFKLL 120
QASFKRMNVD KVIPVEKLVK GRFQDNLDFI QWFKKFYDAN YDGKEYDPVE ARQGQDAIPP 180
PDPGEQIFNL PKKSHHANSP TAGAAKSSPA SKPGSTPSRP SSAKRASSSG SASRSDKDLE 240
TQVIQLNEQV HSLKLALEGV EKERDFYFGK LREIELLCQE HGQENDDLVQ RLMEVLYASD 300
EQEGQTEEPE AEEQAHDQQP QQQEEY 326 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |