CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042259
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Superoxide dismutase [Cu-Zn] 
Protein Synonyms/Alias
  
Gene Name
 Sod1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Cavia porcellus (Guinea pig) 
NCBI Taxa ID
 10141 
Lysine Modification
Position
Peptide
Type
References
132RTMVVHEKPDDLGKGacetylation[1]
Reference
 [1] The cardiac acetyl-lysine proteome.
 Foster DB, Liu T, Rucker J, O'Meally RN, Devine LR, Cole RN, O'Rourke B.
 PLoS One. 2013;8(7):e67513. [PMID: 23844019
Functional Description
 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Copper; Metal-binding; Oxidoreductase; Reference proteome; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 163 AA 
Protein Sequence
MATKAVCVLK GDGPVQGIIH FEQKARPGAE ARGEANGPVV VKGRITGLVE GKHGFHVHEF 60
GDNTQGCTSA GPHFNPLSKK HGGPQDEERH VGDLGNVTAG ADGVANVSIE DSLISLSGAN 120
SIIGRTMVVH EKPDDLGKGG NEESTKTGNA GSRLACGVIG IAQ 163 
Gene Ontology
 GO:0031410; C:cytoplasmic vesicle; IEA:Compara.
 GO:0005829; C:cytosol; IEA:Compara.
 GO:0032839; C:dendrite cytoplasm; IEA:Compara.
 GO:0031012; C:extracellular matrix; IEA:Compara.
 GO:0005615; C:extracellular space; IEA:Compara.
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0043025; C:neuronal cell body; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0043234; C:protein complex; IEA:Compara.
 GO:0005507; F:copper ion binding; IEA:Compara.
 GO:0004784; F:superoxide dismutase activity; IEA:EC.
 GO:0008270; F:zinc ion binding; IEA:Compara.
 GO:0000187; P:activation of MAPK activity; IEA:Compara.
 GO:0008089; P:anterograde axon cargo transport; IEA:Compara.
 GO:0006309; P:apoptotic DNA fragmentation; IEA:Compara.
 GO:0060088; P:auditory receptor cell stereocilium organization; IEA:Compara.
 GO:0007569; P:cell aging; IEA:Compara.
 GO:0006879; P:cellular iron ion homeostasis; IEA:Compara.
 GO:0006302; P:double-strand break repair; IEA:Compara.
 GO:0007566; P:embryo implantation; IEA:Compara.
 GO:0006749; P:glutathione metabolic process; IEA:Compara.
 GO:0060047; P:heart contraction; IEA:Compara.
 GO:0050665; P:hydrogen peroxide biosynthetic process; IEA:Compara.
 GO:0007626; P:locomotory behavior; IEA:Compara.
 GO:0046716; P:muscle cell homeostasis; IEA:Compara.
 GO:0002262; P:myeloid cell homeostasis; IEA:Compara.
 GO:0045541; P:negative regulation of cholesterol biosynthetic process; IEA:Compara.
 GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Compara.
 GO:0060052; P:neurofilament cytoskeleton organization; IEA:Compara.
 GO:0001541; P:ovarian follicle development; IEA:Compara.
 GO:0032287; P:peripheral nervous system myelin maintenance; IEA:Compara.
 GO:0001819; P:positive regulation of cytokine production; IEA:Compara.
 GO:0008217; P:regulation of blood pressure; IEA:Compara.
 GO:0051881; P:regulation of mitochondrial membrane potential; IEA:Compara.
 GO:0040014; P:regulation of multicellular organism growth; IEA:Compara.
 GO:0060087; P:relaxation of vascular smooth muscle; IEA:Compara.
 GO:0019430; P:removal of superoxide radicals; IEA:Compara.
 GO:0048678; P:response to axon injury; IEA:Compara.
 GO:0042493; P:response to drug; IEA:Compara.
 GO:0045471; P:response to ethanol; IEA:Compara.
 GO:0009408; P:response to heat; IEA:Compara.
 GO:0042542; P:response to hydrogen peroxide; IEA:Compara.
 GO:0001895; P:retina homeostasis; IEA:Compara.
 GO:0008090; P:retrograde axon cargo transport; IEA:Compara.
 GO:0007605; P:sensory perception of sound; IEA:Compara.
 GO:0007283; P:spermatogenesis; IEA:Compara.
 GO:0042554; P:superoxide anion generation; IEA:Compara. 
Interpro
 IPR024134; SOD_Cu/Zn_/chaperones.
 IPR018152; SOD_Cu/Zn_BS.
 IPR001424; SOD_Cu_Zn_dom. 
Pfam
 PF00080; Sod_Cu 
SMART
  
PROSITE
 PS00087; SOD_CU_ZN_1
 PS00332; SOD_CU_ZN_2 
PRINTS
 PR00068; CUZNDISMTASE.