Tag | Content |
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CPLM ID | CPLM-018934 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | ATP synthase subunit b, mitochondrial |
Protein Synonyms/Alias | ATPase subunit b; FO-ATP synthase subunit b |
Gene Name | ATPsyn-b |
Gene Synonyms/Alias | ATPsyn-beta; CG8189 |
Created Date | July 27, 2013 |
Organism | Drosophila melanogaster (Fruit fly) |
NCBI Taxa ID | 7227 |
Lysine Modification | Position | Peptide | Type | References |
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144 | SDAIEAEKKEQWRAD | acetylation | [1] |
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Reference | [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation. Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C. Sci Signal. 2011 Jul 26;4(183):ra48. [ PMID: 21791702] |
Functional Description | Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. |
Sequence Annotation | |
Keyword | Alternative splicing; CF(0); Complete proteome; Hydrogen ion transport; Ion transport; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Transit peptide; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 243 AA |
Protein Sequence | MFSRAALLTA QRPLTVAATR SAAAAAAPGG AIERRQRPEH PGKVRLGFLP EEWFQFFYNK 60 TGVTGPYTFG VGLITYLCSK EIYVMEHEYY SGLSLGIMAI IAVKKLGPVI AKWADGEIDK 120 IESEWKEGRE AELKVLSDAI EAEKKEQWRA DGALLLMEAK KENIALQLEA AFRERAMNVY 180 SEVKRRLDYQ VECRHVERRL SQKHMVNWIT TNVLASISPQ QEKETLNKCI ADLSALALRV 240 KSA 243 |
Gene Ontology | GO:0005811; C:lipid particle; IDA:FlyBase. GO:0000276; C:mitochondrial proton-transporting ATP synthase complex, coupling factor F(o); IBA:RefGenome. GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IBA:RefGenome. GO:0015986; P:ATP synthesis coupled proton transport; IBA:RefGenome. GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase. |
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PRINTS | |