UniProt Accession

 PGK_PLAF7; P27362 

Genbank Protein ID

 M59249; AL844508 

Genbank Nucleotide ID

 AAA29727.1; CAD51907.1 

Protein Name

 Phosphoglycerate kinase 

Protein Synonyms/Alias

  

Gene Name

 PGK 

Gene Synonyms/Alias

 PFI1105w 

Created Date

 July 27, 2013 

Organism

 Plasmodium falciparum (isolate 3D7) 

NCBI Taxa ID

 36329 

Lysine Modification

Position	Peptide	Type	References
74	PDGLRNEKYTLKPVA	acetylation	[1]
130	FHIEEEGKGVDANGN	acetylation	[1]
148	ANKEDVEKFQNDLTK	acetylation	[1]
155	KFQNDLTKLADVFIN	acetylation	[1]
405	SLELLEGKELPGVLA	acetylation	[1]

Reference

 [1] Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic development.
 Miao J, Lawrence M, Jeffers V, Zhao F, Parker D, Ge Y, Sullivan WJ Jr, Cui L.
 Mol Microbiol. 2013 Aug;89(4):660-75. [PMID: 23796209] 

Functional Description

  

Sequence Annotation

 NP_BIND 372 375 ATP (By similarity).
 REGION 24 26 Substrate binding (By similarity).
 REGION 63 66 Substrate binding (By similarity).
 BINDING 39 39 Substrate (By similarity).
 BINDING 122 122 Substrate (By similarity).
 BINDING 170 170 Substrate (By similarity).
 BINDING 215 215 ATP.
 BINDING 312 312 ATP; via carbonyl oxygen (By similarity).
 BINDING 343 343 ATP.
 BINDING 374 374 ATP.  

Keyword

 3D-structure; ATP-binding; Complete proteome; Glycolysis; Kinase; Nucleotide-binding; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 416 AA 

Protein Sequence

Gene Ontology

 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004618; F:phosphoglycerate kinase activity; IEA:EC.
 GO:0006096; P:glycolysis; IEA:UniProtKB-UniPathway. 

Interpro

 IPR001576; Phosphoglycerate_kinase.
 IPR015901; Phosphoglycerate_kinase_C.
 IPR015911; Phosphoglycerate_kinase_CS.
 IPR015824; Phosphoglycerate_kinase_N. 

Pfam

 PF00162; PGK 

SMART

  

PROSITE

 PS00111; PGLYCERATE_KINASE 

PRINTS

 PR00477; PHGLYCKINASE.