CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042523
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Probable ATP-dependent RNA helicase DDX60-like 
Protein Synonyms/Alias
  
Gene Name
 DDX60L 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
194MKDLPILKSDDPVVPubiquitination[1, 2]
205PVVPSLFKQKTSDELubiquitination[1]
207VPSLFKQKTSDELLHubiquitination[2, 3]
257DYQQFYGKSLESISTubiquitination[2]
305SKKKSFLKEDQNKAQubiquitination[1]
432PTLIGDDKNKKKYSIubiquitination[1]
542TVENRFTKTLPAGRTubiquitination[2, 3]
737EFILFKNKIVIKKLDubiquitination[2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 868 AA 
Protein Sequence
RMYHRVLVHS NCLSLQEVED FCRLRCLCVA FQLHLPLSQR ACSRVITCSW IRNSDSFLKM 60
NKWCEYFILS NLNVFGCWNL NLNHVSDLYD EQLLKNIAFY YEFESTQEPH LNLGDSIRRD 120
YEDLWNVVSH LVKEFNVGKS FPLRTTRRHF LRQEKSVIQE ISLEKMPSVG FIPMTSAVID 180
EFVGDMMKDL PILKSDDPVV PSLFKQKTSD ELLHWHAQRL LSDDYDRIKC HVDEQSRDPH 240
VLDFLKKIQD YQQFYGKSLE SISTKVIVTQ TTRPKEDSSG ASGEILQNTK PHQITKKSKK 300
KSFLKEDQNK AQQNDDLLFS IEEEMKNNLH SGIRKLEDYL TSCASNSVKF GVEMLGLIAC 360
FKAWKKHCRG EGKISKDLSI AVQMMKRIHS LLERYPEILE AEHHQYIAKC LKYLGFNDLA 420
NSLDPTLIGD DKNKKKYSID IGPARFQLQY MGHYLIRDER KDRDPRVQDF IPNAWQQELL 480
DVVDKNESAV IVAPTSSGKT YASYYCMEKV LRESDVGVVV YVAPAKSLVG QVAATVENRF 540
TKTLPAGRTL CGAFTRDYCH NVLNCQVHYL GREVGAKFWE LLLVIIRCPF LVLSATINNP 600
NLLTKWLQSV KQYWKQADKI MEEKCISEKQ ADKCLNFLQD HSYKNQSYEV RLVLYGERYN 660
DLEKHICSVK HDDVYFDHFH PCAALTTDII EKYGFPPDLT LTPQESIQLY DTMAQVWETW 720
PRAQELCPEE FILFKNKIVI KKLDARKYEE NLKAELTNWI KNGQVKKVKR VLKNLSPDSL 780
SSSKDMVKMF PLLVEKLRQM DKLPAIFFLF KNDDVGKRAG SVCTFLEKTE TKSHPHTECH 840
SYVFAIDEVL EKVRKTQKRI TKKNPKKA 868 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:InterPro. 
Interpro
 IPR011545; DNA/RNA_helicase_DEAD/DEAH_N.
 IPR014001; Helicase_ATP-bd.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00270; DEAD 
SMART
 SM00487; DEXDc 
PROSITE
 PS51192; HELICASE_ATP_BIND_1 
PRINTS