| Tag | Content |
|---|
| CPLM ID | CPLM-000175 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | AMP deaminase 3 |
Protein Synonyms/Alias | AMP deaminase H-type; AMP deaminase isoform E; Heart-type AMPD |
Gene Name | Ampd3 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 431 | ARELEDSKYQYSEPR | ubiquitination | [1] | | 501 | NIFLPLFKATINPQD | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | AMP deaminase plays a critical role in energy metabolism. |
Sequence Annotation | REGION 387 392 Substrate binding (By similarity).
REGION 663 666 Substrate binding (By similarity).
ACT_SITE 607 607 Proton acceptor (By similarity).
METAL 316 316 Zinc; catalytic (By similarity).
METAL 318 318 Zinc; catalytic (By similarity).
METAL 585 585 Zinc; catalytic (By similarity).
METAL 662 662 Zinc; catalytic (By similarity).
BINDING 318 318 Substrate (By similarity).
BINDING 588 588 Substrate (By similarity).
MOD_RES 107 107 Phosphoserine (By similarity). |
Keyword | Complete proteome; Hydrolase; Metal-binding; Nucleotide metabolism; Phosphoprotein; Reference proteome; Zinc. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 766 AA |
Protein Sequence | MPRQFPKLNM SDLDEHVRLL AEKVFAKVLR EEDSKDVMSL FTVPEDCPIG QKEAKERELQ 60
KELAEQKSVE TAKRKKSFKM IRSQSLSLQM PTQQDWKGPP TASPAMSPAT PLVPGATSKP 120
GPAPYAMPEY QRVTISGDYC AGITVEDYEQ AAKSLAKALM IREKYARLAY HRFPRTTAQY 180
LAHQGESVPL EEGLPDFHPP PLPQEDPYCL DDAPPNLGYL VRMHGGVLFV YDNQTMLERQ 240
EPHSLPYPDL ETYIVDMSHI LALITDGPTK TYCHRRLNFL ESKFSLHEML NEMSEFKELK 300
SNPHRDFYNV RKVDTHIHAA ACMNQKHLLR FIKHTYQTEP DRTVAEKLGR KITLRQVFDS 360
LHMDPYDLTV DSLDVHAGRQ TFHRFDKFNS KYNPVGASEL RDLYLKTENY LGGEYFARMV 420
KEVARELEDS KYQYSEPRLS IYGRSPKEWS SLARWFIQHK VYSPNMRWII QVPRIYDIFR 480
SKKLLPNFGK MLENIFLPLF KATINPQDHR ELHLFLKYVT GFDSVDDESK HSDHMFSDKS 540
PSPDLWTSEQ NPPYSYYLYY MYANIMVLNN LRRERGLSTF LFRPHCGEAG SITHLVSAFL 600
TADNISHGLL LKKSPVLQYL YYLAQIPIAM SPLSNNSLFL EYSKNPLREF LHKGLHVSLS 660
TDDPMQFHYT KEALMEEYAI AAQVWKLSTC DLCEIARNSV LQSGLSHQEK QKFLGQNYYK 720
EGPEGNDIRK TNVAQIRMAF RYETLCNELS FLSDAMKSEE ITALTK 766 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |